Cell-Based Therapies in Stroke

  • Jukka Jolkkonen
  • Piotr Walczak

Table of contents

  1. Front Matter
    Pages i-viii
  2. Preclinical Optimization of Cell Therapies

    1. Front Matter
      Pages 1-1
    2. Stanley Hoang, Henry Jung, Tonya Bliss, Gary Steinberg
      Pages 3-14
    3. Alison E. Willing, Md Shahaduzzaman
      Pages 15-28
    4. Travis Dailey, David J. Eve, Naoki Tajiri, Tsz Lau, Yusef Mosley, Harry van Loveren et al.
      Pages 29-46
  3. Translational Imaging Techniques to Study Cell Therapy

    1. Front Matter
      Pages 63-63
    2. Antje Y. Dreyer, Donald Lobsien, Claudia Pösel, Karl-Titus Hoffmann, Björn Nitzsche, Matthias Findeisen et al.
      Pages 105-125
    3. Angela M. Auriat, Helen Nichol, Michael Kelly, Raphael Guzman
      Pages 127-136
    4. Mari Raki, Kim Bergström, Jukka Jolkkonen
      Pages 137-149
  4. Early Phase Clinical Studies

    1. Front Matter
      Pages 151-151
    2. Douglas Kondziolka, Gillian Harrison, Lawrence Wechsler
      Pages 153-170
    3. Osman Mir, Aditya P. Lal, Farhaan Vahidy, Kaushik Parsha, Sean I. Savitz
      Pages 171-179
    4. Gabriel R. de Freitas, Rosália Mendez-Otero
      Pages 181-190
  5. Back Matter
    Pages 203-204

About this book


Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.





cell engineering cell therapy cerebrovascular ischemic stroke

Editors and affiliations

  • Jukka Jolkkonen
    • 1
  • Piotr Walczak
    • 2
  1. 1., Institute of Clinical MedicineUniversity of Eastern FinlandKuopioFinland
  2. 2.School of Medicine, Division of MR ResearchJohns Hopkins UniversityBaltimoreUSA

Bibliographic information

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