Bacterial Lipopolysaccharides

Structure, Chemical Synthesis, Biogenesis and Interaction with Host Cells

  • Yuriy A. Knirel
  • Miguel A. Valvano

Table of contents

  1. Front Matter
    Pages i-xi
  2. Alba Silipo, Antonio Molinaro
    Pages 1-20
  3. Yuriy A. Knirel
    Pages 41-115
  4. Shoichi Kusumoto
    Pages 117-130
  5. Paul Kosma, Alla Zamyatina
    Pages 131-161
  6. Christopher M. Stead, Aaron C. Pride, M. Stephen Trent
    Pages 163-193
  7. Youai Hao, Joseph S. Lam
    Pages 195-235
  8. Uwe Mamat, Mikael Skurnik, José Antonio Bengoechea
    Pages 237-273
  9. Miguel A. Valvano, Sarah E. Furlong, Kinnari B. Patel
    Pages 275-310
  10. Paola Sperandeo, Gianni Dehò, Alessandra Polissi
    Pages 311-337
  11. Monica M. Cunneen, Peter R. Reeves
    Pages 339-370
  12. Georgina L. Hold, Clare E. Bryant
    Pages 371-387
  13. Francesco Peri, Matteo Piazza, Valentina Calabrese, Roberto Cighetti
    Pages 389-416
  14. Gitte Erbs, Mari-Anne Newman
    Pages 417-433
  15. Back Matter
    Pages 435-440

About this book


The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling.


Bacterial Chemical constitution Endotoxin Lipopolysaccharides

Editors and affiliations

  • Yuriy A. Knirel
    • 1
  • Miguel A. Valvano
    • 2
  1. 1.N.D. Zelinsky Institute of Organic ChemiRussian Academy of SciencesMoscow, V-334Russian Federation
  2. 2.Centre for Human Immunology and, Department of Microbiology and ImmunologUniversity of Western OntarioLondonCanada

Bibliographic information

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Chemical Manufacturing