© 2019

Basic Methods Handbook for Clinical Orthopaedic Research

A Practical Guide and Case Based Research Approach

  • Volker Musahl
  • Jón Karlsson
  • Michael T. Hirschmann
  • Olufemi R. Ayeni
  • Robert G. Marx
  • Jason L. Koh
  • Norimasa Nakamura

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Evidence Based Medicine in Orthopaedics

    1. Front Matter
      Pages 1-1
    2. Eleonor Svantesson, Eric Hamrin Senorski, Jón Karlsson, Olufemi R. Ayeni, Kristian Samuelsson
      Pages 3-10
    3. Vishal S. Desai, Christopher L. Camp, Aaron J. Krych
      Pages 11-22
    4. Naomi Roselaar, Magaly Iñiguez Cuadra, Stephen Lyman
      Pages 23-32
    5. Jason L. Koh, Diego Villacis
      Pages 33-42
    6. Michael Hantes, Apostolos Fyllos
      Pages 43-47
    7. Naomi Roselaar, Niv Marom, Robert G. Marx
      Pages 49-54
  3. How to Get Started with Clinical Research?

    1. Front Matter
      Pages 55-55
    2. Lachlan M. Batty, Timothy Lording, Eugene T. Ek
      Pages 57-63
    3. Lukas B. Moser, Michael T. Hirschmann
      Pages 65-73
    4. Karren Takamura, Frank Petrigliano
      Pages 75-81
    5. Yuichi Hoshino, Alfonso Barnechea
      Pages 83-88
    6. Monique C. Chambers, Sarah M. Tepe, Lorraine A. T. Boakye, MaCalus V. Hogan
      Pages 89-95
    7. José F. Vega, Kurt P. Spindler
      Pages 97-109
    8. Andrew Firth, Dianne Bryant, Jacques Menetrey, Alan Getgood
      Pages 111-120
    9. Caroline Mouton, Laura De Girolamo, Daniel Theisen, Romain Seil
      Pages 121-132
    10. Adam J. Popchak, Andrew D. Lynch, James J. Irrgang
      Pages 133-142
  4. Basics in Statistics: Statistics Made Simple!

    1. Front Matter
      Pages 151-151

About this book


This book is designed to meet the needs of both novice and senior researchers in Orthopaedics by providing the essential, clinically relevant knowledge on research methodology that is sometimes overlooked during training. Readers will find a wealth of easy-to-understand information on all relevant aspects, from protocol design, the fundamentals of statistics, and the use of computer-based tools through to the performance of clinical studies with different levels of evidence, multicenter studies, systematic reviews, meta-analyses, and economic health care studies. A key feature is a series of typical case examples that will facilitate use of the volume as a handbook for most common research approaches and study types. Younger researchers will also appreciate the guidance on preparation of abstracts, poster and paper presentations, grant applications, and publications. The authors are internationally renowned orthopaedic surgeons with extensive research experience and the book is published in collaboration with ISAKOS.


Manuscript writing Clinical research practice Study Scientific meeting Scientific article Research methodology

Editors and affiliations

  • Volker Musahl
    • 1
  • Jón Karlsson
    • 2
  • Michael T. Hirschmann
    • 3
  • Olufemi R. Ayeni
    • 4
  • Robert G. Marx
    • 5
  • Jason L. Koh
    • 6
  • Norimasa Nakamura
    • 7
  1. 1.UPMC Rooney Sports ComplexUniversity of PittsburghPittsburghUSA
  2. 2.Department of Orthopaedics, Sahlgrenska AcademyGothenburg University, Sahlgrenska University HospitalGothenburgSweden
  3. 3.Department of Orthopaedic Surgery and TraumatologyKantonsspital Baselland (Bruderholz, Laufen und Liestal)BruderholzSwitzerland
  4. 4.McMaster UniversityHamiltonCanada
  5. 5.Hospital for Special SurgeryNew YorkUSA
  6. 6.Department of Orthopaedic SurgeryNorthShore University HealthSystemEvanstonUSA
  7. 7.Institute for Medical Science in SportsOsaka Health Science UniversityOsakaJapan

About the editors

Volker Musahl, MD, is Associate Professor of Orthopaedic Surgery at the University of Pittsburgh School of Medicine, Associate Professor of Bioengineering at the University of Pittsburgh's Swanson School of Engineering, Program Director of the Sports Medicine fellowship program, and Medical Director of the UPMC Center for Sports Medicine. Dr. Musahl has received various honors and awards and in 2015 was appointed Assistant Editor-in-Chief of Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA). His research interests include knee and shoulder biomechanics. 

Jon Karlsson, MD, PhD, is Professor of Orthopaedics and Sports Traumatology at Sahlgrenska Academy, Gothenburg University, Sweden, where he is a Senior Consultant and Academic Head of the Orthopaedic Department. He is the editor or author of more than 300 papers and 30 textbooks in Orthopaedics and Sports Traumatology. He has held important positions in both ESSKA and ISAKOS and is currently Editor-in-Chief of Knee Surgery, Sports Traumatology, Arthroscopy (KSSTA). 

Michael T. Hirschmann, MD, is Leading Consultant in Head and Knee Surgery, Department of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland, Switzerland. He was awarded his Habilitation “venia docendi” from the University of Basel in 2012. Dr. Hirschmann is a member of the Executive Committee of the Gesellschaft für Arthroskopie und Gelenkchirurgie and Secretary General of European Knee Associates. He is a member of the editorial boards of various journals, including KSSTA and World Journal of Orthopedics

Olufemi R. Ayeni, MD, MSc, FRCSC, is Associate Professor in the Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada. He is also Director of MacSports, Division of Orthopaedic Surgery, McMaster University. Dr. Ayeni is an ISAKOS Scientific Committee Member. He acts as a reviewer for a number of leading journals in Orthopaedics and Sports Medicine and is lead or co-author of over 150 peer-reviewed journal articles. 

Robert G. Marx, MS, MSc, is Attending Orthopaedic Surgeon at the Hospital for Special Surgery, Weill Cornell Medical College, New York, where he is Professor of Orthopaedic Surgery and Professor of Public Health. He is also Director of the Foster Center for Clinical Outcome Research, Hospital for Special Surgery. He is a former member of the Board of Directors of ISAKOS and has served as Chair of the ISAKOS Scientific Advisory Committee. Dr. Marx is the author of four books and 210 peer-reviewed articles. 

Jason Lee Koh, MD, MBA, is Chairman of the Department of Orthopaedic Surgery and Clinical Director of the Orthopaedic Institute at NorthShore University HealthSystem, Chicago. He is also Clinical Professor of Surgery at University of Chicago Pritzker School of Medicine. In 2012 he received the prestigious Charles Neer Award from the American Shoulder and Elbow Society. Dr. Koh has sat on numerous committees and is a member of the Board of Councilors of the American Academy of Orthopaedic Surgery. 

Norimasa Nakamura, MD, PhD, is an orthopaedic surgeon and Professor at the Institute for Medical Science in Sports, Osaka Health Science University, Osaka City, Japan. Dr. Nakamura is a Fellow of the Royal College of Surgeons (FRCS) (England). He is President of the International Cartilage Repair Society (ICRS) and a former chair of the Scientific Committee of ISAKOS. He is a member of the editorial boards of various leading journals in the field of Orthopaedics and author of more than 120 peer-reviewed papers.

Bibliographic information

  • Book Title Basic Methods Handbook for Clinical Orthopaedic Research
  • Book Subtitle A Practical Guide and Case Based Research Approach
  • Editors Volker Musahl
    Jón Karlsson
    Michael T. Hirschmann
    Olufemi R. Ayeni
    Robert G. Marx
    Jason L. Koh
    Norimasa Nakamura
  • DOI
  • Copyright Information ISAKOS 2019
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-662-58253-4
  • eBook ISBN 978-3-662-58254-1
  • Edition Number 1
  • Number of Pages XIV, 584
  • Number of Illustrations 28 b/w illustrations, 93 illustrations in colour
  • Topics Surgical Orthopedics
    Conservative Orthopedics
    Sports Medicine
  • Buy this book on publisher's site
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