Blistering Diseases

Clinical Features, Pathogenesis, Treatment

  • Dédée F. Murrell

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Pathogenesis

    1. Front Matter
      Pages 1-1
    2. Sana Hashmi, M. Peter Marinkovich
      Pages 3-20
    3. Karlin Karlmark, Rüdiger Eming
      Pages 21-33
    4. Mor Miodovnik, Eli Sprecher
      Pages 35-47
    5. Flor Evangelista, Donna A. Culton, Luis A. Diaz
      Pages 55-65
    6. Cristina Has, Leena Bruckner-Tuderman
      Pages 67-75
    7. Johann W. Bauer, Alfred Klausegger
      Pages 77-84
    8. Cristina Has
      Pages 103-110
    9. Ningning Dang, Dédée F. Murrell
      Pages 111-120
    10. Ralf J. Ludwig, Detlef Zillikens
      Pages 121-130
    11. Enno Schmidt, Luca Borradori, Eli Sprecher, Branka Marinovic, Animesh A. Sinha, Pascal Joly
      Pages 131-139
    12. David S. Rubenstein, Carlo Pincelli
      Pages 141-152
  3. Diagnostic Tests

    1. Front Matter
      Pages 153-153
    2. Daisuke Tsuruta, Takashi Hashimoto
      Pages 193-201

About this book


This book is a comprehensive compendium of current knowledge on inherited and autoimmune blistering diseases that relates advances in our understanding of the pathogenetic mechanisms to management of the individual diseases. The aim is to provide a detailed reference for dermatologists who care for patients with these conditions and a useful “one-stop information shop” for specialists outside of dermatology. The book opens by describing the structure and biology of the epidermis and basement membrane zone and discussing the genes and proteins that are targets for mutations and autoantibodies. The role of the various diagnostic tests is explained, and clinical manifestations of the specific diseases are presented with the aid of many high-quality illustrations. The forms of treatment appropriate in specific conditions are then described in depth, with coverage of dressings, drugs, surgical procedures, gene therapy, and other novel approaches. Helpful algorithms are included both for testing and monitoring and for treatment.


Epidermolysis bullosa Immunofluorescence Lamina densa disorders Pemphigoid Pemphigus

Editors and affiliations

  • Dédée F. Murrell
    • 1
  1. 1.Department of DermatologySt George Hospital, University of New South WalesSydneyAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-662-45697-2
  • Online ISBN 978-3-662-45698-9
  • About this book
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