Metronomic Chemotherapy

1. Clinical Pharmacology of Metronomic Chemotherapy

   1. Metronomics: Potential Social Impact and New Business Models to Improve Availability of Cancer Treatments

      • Yuliya Snihur, Eddy Pasquier, Graciela Scharovsky, Nicolas Andre

      Pages 247-261

   2. Adverse Side Effects Associated with the Use of Low-Dose Metronomic Chemotherapy

      • Keemo Delos Santos, Kelly Lien, Soley Georgsdottir, Lavarnan Sivanathan, Urban Emmenegger

      Pages 263-279

2. Metronomic Chemotherapy in Veterinarian Clinic

   1. Front Matter

      Pages 281-281

      PDF

   2. Clinical Studies of Metronomic Chemotherapy in Dogs

      • Veronica Marchetti, Mario Giorgi

      Pages 283-295

This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

• Antiangiogenic drugs
• Cancer
• Metronomic chemotherapy
• Pharmacology

• Division of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

  Guido Bocci

• Department of Biological Sciences, University of Texas at El Paso, El Paso, USA

  Giulio Francia

Policies and ethics