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Monoclonal Antibodies in Transplantation

  • Lucienne Chatenoud

Part of the Medical Intelligence Unit book series (MIU.LANDES)

Table of contents

  1. Front Matter
    Pages N2-xi
  2. Mary Ann Simpson, Anthony P. Monaco
    Pages 1-19
  3. Daniel Abramowicz, Michel Goldman
    Pages 99-135
  4. Alain Fischer, M. Cavazzana-Calvo, N. Jabado, S. Sarnacki
    Pages 137-153
  5. Lucienne Chatenoud, Michelle Webb, Jean-François Bach
    Pages 155-182
  6. Back Matter
    Pages 183-190

About this book

Introduction

Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection. Moreover, the data leads us to hope that the use of these new therapeutic agents may allow the induction of specific tolerance to transplant alloantigens which is the only means to avoid the major risks of sustained immunosuppression, namely an increased susceptibility to infection and tumor development. In this volume the editors combine contributions dealing with very practical aspects of the clinical use of monoclonal antibodies with a more general discussion on the developments one may foresee in the near future.

Keywords

Antigen ICAM1 adhesion allograft bone marrow transplantation cyctokines immunological tolerance immunosuppression immunotherapy infection molecules rejection transplantation

Authors and affiliations

  • Lucienne Chatenoud
    • 1
  1. 1.INSERM U25Hôpital NeckerParisFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-22195-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-22197-6
  • Online ISBN 978-3-662-22195-2
  • Series Print ISSN 1080-3645
  • Buy this book on publisher's site
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