© 1998

The Biology of Germinal Centers in Lymphoid Tissue


Table of contents

  1. Front Matter
    Pages i-xi
  2. J. G. Tew, D. Qin, J. Wu, G. F. Burton, A. K. Szakal
    Pages 105-129
  3. R. A. Insel, M. H. Nahm
    Pages 131-164
  4. V. K. Tsiagbe, N. M. Ponzio, G. S. Erianne, D. J. Zhang, G. J. Thorbecke, G. Inghirami
    Pages 199-234
  5. Back Matter
    Pages 235-241

About this book


This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.


Antigen B lymphocytes Lymphozyten biology cell development genes immunoglobulin influence lymphocytes lymphoid tissue lymphoma mutation retroviruses tissue

Authors and affiliations

  1. 1.Department of PathologyNew York University Medical Center and Kaplan Comprehensive Cancer CenterNew YorkUSA

Bibliographic information

  • Book Title The Biology of Germinal Centers in Lymphoid Tissue
  • Editors G. Jeanette Thorbecke
    Vincent K. Tsiagbe
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-64559-7
  • Softcover ISBN 978-3-662-13143-5
  • eBook ISBN 978-3-662-13141-1
  • Edition Number 1
  • Number of Pages XI, 241
  • Number of Illustrations 15 b/w illustrations, 6 illustrations in colour
  • Additional Information Jointly published with Landes Bioscience, Georgetown, USA
  • Topics Immunology
    Cancer Research
    Cell Biology
    Molecular Medicine
  • Buy this book on publisher's site
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