Tacrolimus Ointment

A Topical Immunomodulator for Atopic Dermatitis

  • Thomas Ruzicka
  • Sakari Reitamo

Table of contents

  1. Front Matter
    Pages I-XX
  2. Atopic Dermatitis

    1. Front Matter
      Pages 1-1
    2. T. L. Diepgen
      Pages 3-21
  3. Development of Tacrolimus Ointment

    1. Front Matter
      Pages 80-80
    2. T. Goto, H. Nakagawa
      Pages 81-98
    3. T. Assmann, B. Homey, T. Ruzicka
      Pages 111-126
  4. Clinical Experience with Tacrolimus Ointment in Atopic Dermatitis

    1. Front Matter
      Pages 128-128
    2. S. Reitamo
      Pages 129-160
    3. Y. de Prost
      Pages 161-183
    4. T. Assmann, T. Ruzicka
      Pages 213-233
  5. Social Impact of Atopic Dermatitis

    1. Front Matter
      Pages 235-235
    2. A. Y. Finlay, W. H. C. Burgdorf
      Pages 237-254
    3. M. Augustin
      Pages 255-270
  6. Back Matter
    Pages 271-279

About this book


Therapeutic break-through's in medicine are usually accompanied by a wealth of data. Often they result in a change of disease treatment paradigms. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. This book gives an easy-to-read overview of the discovery and the development of Tacrolimus ointment for the treatment of atopic dermatitis. Summarising the largest clinical trial program ever conducted in dermatology for a new treatment with more than 13000 patients, it offers a detailed insight into the efficacy and safety profile of Tacrolimus ointment. Based on this large body of data and extensive personal experience, the authors offer practical and hands-on guidance for the physician as to when and how to use Tacrolimus ointment in daily practice.


Dermatitis Dermatologie Neurodermitis dermatology epidemiology skin

Editors and affiliations

  • Thomas Ruzicka
    • 1
  • Sakari Reitamo
    • 2
  1. 1.Universitätsklinikum Düsseldorf HautklinikHeinrich-Heine-UniversitätDüsseldorfGermany
  2. 2.Hospital for Skin and Allergic Diseases, Department of DermatologyHelsinki University Central HospitalHelsinkiFinland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2004
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-10211-4
  • Online ISBN 978-3-662-10209-1
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology
Consumer Packaged Goods