Physiology and Pharmacology of Biological Rhythms

  • Peter H. Redfern
  • B. Lemmer

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 125)

Table of contents

  1. Front Matter
    Pages I-XXIV
  2. E. Haus, Y. Touitou
    Pages 95-134
  3. K. Witte, B. Lemmer
    Pages 135-156
  4. P. M. Bélanger, B. Bruguerolle, G. Labrecque
    Pages 177-204
  5. M. H. Smolensky, G. E. D’Alonzo
    Pages 205-249
  6. B. Lemmer, F. Portaluppi
    Pages 251-297
  7. L. Mejean, A. Stricker-Krongrad, A. Lluch
    Pages 333-350
  8. J. G. Moore, H. Merki
    Pages 351-373
  9. G. D. Block, S. Michel
    Pages 435-455
  10. A. M. Rosenwasser, A. Wirz-Justice
    Pages 457-486
  11. F. Andreotti, G. Patti
    Pages 533-555
  12. J. Cambar, M. Pons
    Pages 557-588
  13. B. Bruguerolle
    Pages 607-618
  14. G. Labrecque, M. Karzazi, M.-C. Vanier
    Pages 619-649
  15. Back Matter
    Pages 651-668

About this book


Measured by any criteria, research in chronobiology in general and chronopharmacology in particular has expanded rapidly in recent years. This expansion has been paralleled by an increasing recognition by those outside the field of the relevance and significance of recent developments in chronobiology. Advances in two areas have been chiefly responsible. First, application of the full range of modern techniques in behavioral, neurochemical, and molecular biology have greatly improved our understanding of basic clock mechanisms. In several species the genetic basis of the circadian clock is being progressively delineated. A complete picture of the neurochemical and neuroanatomical structure of the mammalian clock is emerging and the complex pattern of control mechanisms involving endogenous clock mechan­ isms and photic and nonphotic zeitgebers is being built up as a result of behavioral studies. Secondly, in parallel with these exciting developments in basic science, clinical applications are being convincingly demonstrated in the general fields of pharmacology and medicine as well as in specific areas, e.g., jet lag, shiftwork maladaption syndrome, blindness, and cardiovascular system. It is therefore an opportune time to review progress in the field of chronopharmacology and to introduce some of the exciting developments and prospects to a readership beyond the confines of the chronobiological cognoscenti. This volume is therefore aimed primarily at the pharmacologist - whether basic, applied, or clinical-who is not a specialist in chronobiology.


Asthma Biorhythmus Chronopharmakologie Nervous System anatomy biological clocks biological rhythms chronopharmacology chronotherapeutics circadian rhythms metabolism physiology

Editors and affiliations

  • Peter H. Redfern
    • 1
  • B. Lemmer
    • 2
  1. 1.School of Pharmacy and PharmacologyUniversity of BathBathUK
  2. 2.Instituts für Pharmakologie und Toxikologie Fakultät für klinische Medizin MannheimUniversität HeidelbergMannheimGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-08265-8
  • Online ISBN 978-3-662-09355-9
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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