Mechanisms in Carcinogenesis and Cancer Prevention

  • Harri U. Vainio
  • Eino K. Hietanen

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 156)

Table of contents

  1. Front Matter
    Pages I-XXI
  2. H. Vainio, E. Hietanen
    Pages 1-11
  3. H. Ohgaki, W. Yasui, J. Yokota
    Pages 25-39
  4. M. M. Manson, L. M. Howells, E. A. Hudson
    Pages 41-56
  5. E. Gormally, P. Hainaut
    Pages 57-81
  6. B. W. Stewart
    Pages 83-106
  7. R. Kaaks
    Pages 141-167
  8. G. J. Kelloff, C. C. Sigman
    Pages 187-210
  9. F. X. Bosch, S. de Sanjosé, J. Ribes, C. A. González
    Pages 229-251
  10. O. Pelkonen, K. Vähäkangas, H. Raunio
    Pages 253-269
  11. C. Gerhäuser, N. Frank
    Pages 289-305
  12. Back Matter
    Pages 323-329

About this book


A large proportion of cancers is preventable. External factors, discovered by epidemiological studies during the last 50 years, account for a majority of all cancer deaths. However, still rather little is known, about how environmental and genetic factors interact, how they may regulate gene activation etc. And it is a long way from the discovery of a basic regulatory mechanism to practical patient treatment. This volume describes the present state of the art in carcinogenesis, possibilities for cancer prevention, and gives genetic background in cancer development. Attention is given to the host-environment interaction, considering how this interaction may lead to cancer formation and how it can be utilised in cancer prevention. The molecular basis for cancer development and the molecular basis for prevention are described.


angiogenesis apoptosis cancer genomics cancer prevention carcinogenesis lead xenobiotics

Editors and affiliations

  • Harri U. Vainio
    • 1
  • Eino K. Hietanen
  1. 1.Unit of ChemopreventionInternational Agency for Research on CancerLyonFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-07859-0
  • Online ISBN 978-3-662-08602-5
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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