© 2003

Epilepsy as a Dynamic Disease

  • John Milton
  • Peter Jung


  • The first book to bring together experts in epilepsy, bio-engineering, and dynamical systems theory to discuss the possibility of treating epilepsy by controlling the mechanisms that cause seizures

  • Includes a unique reference database with more than 1000 references, including hard-to-access references in the Russian literature

  • A website will be provided


Part of the Biological and Medical Physics Series book series (BIOMEDICAL)

Table of contents

  1. Front Matter
    Pages I-XXXII
  2. J. Milton
    Pages 1-14
  3. S. A. Chkhenkeli, J. Milton
    Pages 25-36
  4. P. Jung, A. H. Cornell-Bell, A. deGrauw, R. Strawsburg
    Pages 37-49
  5. V. L. Towle, F. Ahmad, M. Kohrman, K. Hecox, S. Chkhenkeli
    Pages 69-81
  6. P. C. Bressloff, S. Coombes
    Pages 83-114
  7. Robert Savit
    Pages 213-235
  8. K. K. Jerger, T. I. Netoff, J. T. Francis, T. Sauer, L. Pecora, S. L. Weinstein et al.
    Pages 237-247
  9. B. J. Gluckman, S. J. Schiff
    Pages 263-282
  10. M. L. Spano, W. L. Ditto, K. Dolan, F. Moss
    Pages 297-322

About this book


A "brain defibrillator" may be closer than we think. An epileptic seizure involves a paroxysmal change in the activity of millions of neurons. Feedback control of seizures would require an implantable device that could predict seizure occurrence and then deliver a stimulus to abort it. To examine the feasibility of building such a device, this text brings together experts in epilepsy, bio-engineering, and dynamical systems theory. Topics include the development of epileptic systems, seizure prediction, neural synchronization, wave phenomena in excitable media, and the control of complex neural dynamics using brief electrical stimuli.


Control Defibrillator Excitable Media Prediction Radiologieinformationssystem Synchronization brain dynamics electroencephalography (EEG) epilepsy neurons

Editors and affiliations

  • John Milton
    • 1
  • Peter Jung
    • 2
  1. 1.Department of NeurologyUniversity of ChicagoChicagoUSA
  2. 2.Department of Physics and Astronomy and Institute for Quantitative BiologyOhio UniversityAthensUSA

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