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© 2020

Chemoselective Nucleophilic α-Amination of Amides

Book
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Part of the BestMasters book series (BEST)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Miran Lemmerer
    Pages 1-9
  3. Miran Lemmerer
    Pages 11-24
  4. Miran Lemmerer
    Pages 25-26
  5. Miran Lemmerer
    Pages 27-55
  6. Back Matter
    Pages 57-60

About this book

Introduction

α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team.

Contents
  • Traditional Umpolung Reactions in Organic Chemistry
  • Insight into Electrophilic Amide Activation
  • Results and Discussion of a New α-Amination Method via Umpolung of Amides
  • α-Arylation of Carbonlys via a Smiles Rearrangement
Target Groups
Scientists and students in the field of organic chemistry, especially in methodology development

The Author
Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria. 

Keywords

α-Amination Organic Chemistry Amide Electrophilic Amide Activation Amine Umpolung Reaction Chemoselective Synthesis N-Oxide Smiles Rearrangement Atom Economic Rearrangement Sulfonamide

Authors and affiliations

  1. 1.Institute of Organic ChemistryUniversity of ViennaViennaAustria

About the authors

Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria. 

Bibliographic information

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