Experimental Investigations into Sarcomas

Therapy Using Ferromagnetically Induced Cytostatics

  • Manfred Georg Krukemeyer

Table of contents

  1. Front Matter
    Pages I-XII
  2. Manfred Georg Krukemeyer
    Pages 1-4
  3. Manfred Georg Krukemeyer
    Pages 5-22
  4. Manfred Georg Krukemeyer
    Pages 23-45
  5. Manfred Georg Krukemeyer
    Pages 47-83
  6. Manfred Georg Krukemeyer
    Pages 85-96
  7. Manfred Georg Krukemeyer
    Pages 97-98
  8. Back Matter
    Pages 99-122

About this book


Manfred Georg Krukemeyer first describes magnetic drug targeting, by which is meant the focused application of drugs, e.g. the introduction of a cytostatic, and which is aimed at optimising its locally therapeutic effect. The author thus achieves a high concentration of cytostatic at the site of the tumour. The particles have to be large enough to be attracted by a magnetic field and so find their way into the tumour, where they release their active ingredient. The aim of the hypothesis formed by one of the author’s study groups was to show in a scientific experiment that in this case cytostatics coupled with iron particles [Fe3O4] can be introduced into a tumour. The focused introduction of drugs – magnetic drug targeting – results in faster arrival of the active ingredient at the target site together with a reduced quantity of active substances. For this reason magnetic drug targeting is also interesting from an economic point of view.

  • Sarcomas and their Pathology 
  • Magnetic Drug Targeting
  • Animal Testing and Patient Examination, Tumour Therapy in Humans 
Target groups
  • Researchers, teachers and students in surgical and oncology departments
  • Doctors working in the fields of surgery and oncology 
About the author
Dr. med. Manfred Georg Krukemeyer is a specialist surgeon currently holding a senior position at a large German hospital enterprise.


Nanomedicine Magnetic drug targeting Biodistribution of mitoxantrone Animal testing Dose effectiveness study Tumour therapy in humans Sarcomas Biodistribution of nanoparticles Ferromagnetically induced cytostatics Cytostatic

Authors and affiliations

  • Manfred Georg Krukemeyer
    • 1
  1. 1.Paracelsus-Klinik OsnabrückGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Fachmedien Wiesbaden GmbH 2018
  • Publisher Name Springer, Wiesbaden
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-658-20590-4
  • Online ISBN 978-3-658-20591-1
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology
Surgery & Anesthesiology