Photopolymerizable Porous Polyorganophosphazenes

Degradable Matrices for Tissue Engineering

  • Tamara Bernadette Aigner

Part of the BestMasters book series (BEST)

Table of contents

  1. Front Matter
    Pages I-XIX
  2. Tamara Bernadette Aigner
    Pages 1-1
  3. Tamara Bernadette Aigner
    Pages 3-13
  4. Tamara Bernadette Aigner
    Pages 15-33
  5. Tamara Bernadette Aigner
    Pages 35-66
  6. Tamara Bernadette Aigner
    Pages 67-68
  7. Back Matter
    Pages 69-75

About this book

Introduction

Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

Contents

  • Polyphosphazenes as Biocompatible and Biodegradable Polymers
  • Functionalization and Crosslinking with Thiol-ene Chemistry
  • Matrix Formation Using a Photocrosslinking Particulate-Leaching Technique
  • Tailored Physical and Biochemical Properties by Blending

Target Groups

  • Researchers and students in the field of chemistry and biology with a focus on polymerchemistry and tissue engineering

The Author

Tamara Bernadette Aigner completed her master’s thesis in biological chemistry at Johannes Kepler University in Linz and South Bohemian University in České Budĕjovice.

Keywords

Degradable Polymer Photo-Crosslinking Polyphosphazene Thiol-ene Chemistry Tissue Engineering

Authors and affiliations

  • Tamara Bernadette Aigner
    • 1
  1. 1.University of BayreuthBayreuthGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-658-09320-4
  • Copyright Information Springer Fachmedien Wiesbaden 2015
  • Publisher Name Springer Spektrum, Wiesbaden
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-658-09319-8
  • Online ISBN 978-3-658-09320-4
  • About this book
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