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Infection Control in Intensive Care Units by Selective Decontamination

The Use of Oral Non-Absorbable and Parenteral Agents

  • Hendrik K. F. van Saene
  • C. P. Stoutenbeek
  • Peter Lawin
  • I. McA. Ledingham
Conference proceedings

Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 7)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Foreword

    1. I. McA. Ledingham
      Pages 1-1
  3. Introduction

    1. H. K. F. van Saene
      Pages 3-4
  4. Pathogenesis

    1. Front Matter
      Pages 5-5
    2. Host Microorganism Relationship in Healthy People

      1. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 25-26
    3. Host Microorganism Relationship in the Critically Ill

  5. The Conventional Approach to Infection Control

    1. Front Matter
      Pages 51-51
    2. Clinical Studies

    3. Antibiotic Resistance

      1. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 83-84
  6. An Alternative Approach — Selective Decontamination of the Digestive Tract (SDD); the Use of Non-absorbable and Parenteral Agents

    1. Front Matter
      Pages 85-85
    2. R. G. Finch, K. Unertl
      Pages 87-87
    3. H. K. F. van Saene, C. P. Stoutenbeek, D. F. Zandstra
      Pages 88-94
    4. C. P. Stoutenbeek
      Pages 95-101
    5. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
      Pages 113-114
    6. Clinical Studies

    7. Role of Endotoxin

      1. J. J. M. van Saene, C. P. Stoutenbeek, H. K. F. van Saene
        Pages 128-134
      2. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 143-144
    8. Emergence of Resistance during SDD

      1. M. Sydow, H. Burchardi, T. A. Crozier, R. Rüchel, C. Busse, W. Seyde
        Pages 155-155
      2. A. E. Murray
        Pages 156-157
      3. E. A. E. Verhage, A. J. H. Kerver, J. H. Rommes
        Pages 159-159
      4. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 160-162
  7. Stress Ulcer Prophylaxis and Pneumonia

    1. Front Matter
      Pages 163-163
    2. Stress Ulcer Prophylaxis and Pneumonia

      1. D. F. Zandstra, C. P. Stoutenbeek, H. M. Oudemans-van Straaten
        Pages 166-172

About these proceedings

Introduction

Selective decontamination is a technique which combines short-term and long-term antimicrobials to prevent or treat the acquisition and subsequent carriage of microorganisms causing late colonization and infections. The antimicrobials are selective in that they leave the indigenous, mostly anaerobic flora more or less intact, whilst the effective decontamination provides a genuine breakthrough in the endogenous route of pathogenesis. The improvements in decontamination techniques presented here offer significant reduction in infection related morbidity and mortality among trauma patients.

Keywords

Sepsis Trauma care infection intensive care intensive care unit mortality multiple organ failure prevention

Editors and affiliations

  • Hendrik K. F. van Saene
    • 1
  • C. P. Stoutenbeek
    • 2
  • Peter Lawin
    • 3
  • I. McA. Ledingham
    • 4
  1. 1.Medical Microbiology, RoyalLiverpool HospitalLiverpoolUK
  2. 2.Intensieve ZorgenOnze Lieve Vrouw GasthuisAmsterdamThe Netherlands
  3. 3.Klinik für Anästhesiologie und operative IntensivmedizinWestfälischen Wilhelms-UniversitätMünsterGermany
  4. 4.The Faculty of MedicineHealth Sciences UniversityAl AinUnited Arab Emirates

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-83752-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-51041-3
  • Online ISBN 978-3-642-83752-4
  • Series Print ISSN 0933-6788
  • Buy this book on publisher's site
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Pharma
Health & Hospitals
Biotechnology