Vascular Perfusion in Cancer Therapy

  • Konrad Schwemmle
  • Karl Aigner

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 86)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Selective Embolization and Organ Perfusion with Cytostatics

    1. S. Bengmark, Å. Andrén-Sandberg
      Pages 13-14
    2. J.-H. Beyer, H. W. von Heyden, H.-H. Bartsch, M. Klee, G. A. Nagel, R. Schuster et al.
      Pages 33-36
    3. F. W. Schumacher, J. Hunold, S. Bayindir
      Pages 41-43
    4. J. Hunold, F. W. Schumacher, S. Bayindir
      Pages 44-45
    5. Back Matter
      Pages 48-48
  3. Intra-Arterial Liver Perfusion

  4. Isolated Liver Perfusion

    1. F. Ghussen, K. Nagel, W. Isselhard
      Pages 93-98
    2. K. Aigner, H. Walther, J. Tonn, A. Wenzl, R. Hechtel, G. Merker et al.
      Pages 99-102
    3. J. Biscoping, F. Mikus, G. Hempelmann
      Pages 110-115
    4. Back Matter
      Pages 121-121
  5. Selective Organ Perfusion with Cytostatics

  6. Tumortherapy with Hyperthermia

  7. Vascular Perfusion in Cancer Therapy of the Extremities

    1. A. Azzarelli, L. Gennari, G. Bonfanti, R. Audisio, V. Quagliuolo
      Pages 218-221
    2. Back Matter
      Pages 222-222
  8. Isolated Perfusion of the Extremities

    1. J. Tonak, W. Hohenberger, F. Weidner, H. Göhl
      Pages 229-238
    2. K. Aigner, P. Hild, K. Henneking, E. Paul, M. Hundeiker
      Pages 239-245
    3. K. Henneking, K. Aigner, C. Deeg, G. Merker, H. W. Spelz, M. Hundeiker
      Pages 254-259
    4. R. P. Braat, J. Wieberdink, E. van Slooten, G. Olthuis
      Pages 260-263
    5. F. J. Lejeune, T. Deloof, P. Ewalenko, J. Fruhling, M. Jabri, M. Mathieu et al.
      Pages 268-276

About this book


Substantial relief of discomfort may be anticipated by most patients suffering from pelvic and lower-extremity pain who are treated by arterial infusion of nitrogen mustard. Seventy-three patients with intractable pain secondary to malignancy arising in the pelvis received 83 percutaneous pelvic arterial infusions of this drug. Sixty infusions (72%) resulted in marked relief from pain for periods averaging 6-8 weeks. Advantages of the procedure are low toxicity, relative simplicity and availability of technique, and an acceptable rate of complications with minimal morbidity. Patients experiencing satisfactory results may expect significant relief from a second infusion for recurrent pain. The most rewarding result is the freedom from the cyclic return of pain characterized by oral and intramuscular analgesic therapy. Little or no relief can be expected in patients with pain caused by compression fractures of the vertebrae, or where the tumor burden is so great that adequate perfusion of the involved nerves is not possible. One should consider this procedure for controlling pain before resorting to the more dangerous and potentially disabling techniques of spinal cordotomy or intrathecal alcohol injection. References Bateman JR, Hazen JG, Stolinsky DC, Steinfeld JL (1966) Advanced carcinoma of the cervix treated by intra-arterial methotrexate. Am J Obstet Gynecol 96: 181-187 Calabresi P, Parks RW Jr (1970) Alkylating agents, antimetabolites, hormones. and other antiproliferative agents. In: Goodman LS, Gilman A (eds) The pharmacological basis of therapeutics, 4th edn.


Zytostatikum alcohol cancer cancer therapy carcinoma chemoembolization chemotherapy hormones liver tumor morbidity pain pharmacology quality of life surgery tumor

Editors and affiliations

  • Konrad Schwemmle
    • 1
  • Karl Aigner
    • 1
  1. 1.Allgemeinchirurgische Klinik des Zentrums für ChirurgieJustus-Liebig-UniversitätGiessenGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1983
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-82027-4
  • Online ISBN 978-3-642-82025-0
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site
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Oncology & Hematology