© 1996

Invertebrate Immunology

  • B. Rinkevich
  • W. E. G. Müller

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 15)

Table of contents

  1. Front Matter
    Pages I-XIII
  2. E. L. Cooper
    Pages 10-45
  3. S. Srimal
    Pages 88-100
  4. P. B. Armstrong, J. P. Quigley
    Pages 101-130
  5. S. E. Fryer, C. J. Bayne
    Pages 131-153
  6. T. Muta, S. Iwanaga
    Pages 154-189
  7. N. Parrinello
    Pages 190-217
  8. Y. Saito
    Pages 218-234
  9. Back Matter
    Pages 249-250

About this book


The biological bases of invertebrate immune responses have interested scientists for decades, from the first relevant observation by E. Metchnikoff in 1882, who discovered phagocytosis while studying starfish larvae. Invertebrate immunology first began to be appre­ ciated as an important field in the late 1960s and 1970s. However, in the following years there was much controversy regarding the question: do invertebrates offer insight into the origin of the sophisticated immune responses of the vertebrates? There are several reasons why progress in research on invertebrate immune competence has been painfully slow. One of the main impediments to the progress, as compared to the fast development of knowledge in the vertebrate systems, was the fact that most of the studies concentrated on "whole organism" assays, mainly on grafting tissues between allogeneic partners. Only in the last few years have more and more aspects of invertebrate immunity been investigated on the cellular, biochemical and molecular levels. These studies led to discoveries of novel defense reactions, new pathways of effector mechanisms which are elicited after recognition of "nonself', and complex, sometimes highly polymorphic genetic elements that control invertebrate immune reactions. The importance of invertebrate immunity for understanding "immunology" as a whole, despite the conflicting models and hypotheses, is now much more recognized than before. Although most of the 20 phyla belonging to the inver­ tebrates have different modes of life, body organizations, habitats occupied, and biochemical patterns, they show striking aspects of exceptional precision for discriminating between self and nonself.


Immunologie Interverteberates Marine Biology Marine Organismen Marine Organisms Meeresbiologie Wirbellose Zellbiologie biology cell cell biology immune response immunity immunology

Editors and affiliations

  • B. Rinkevich
    • 1
  • W. E. G. Müller
    • 2
  1. 1.Israel Oceanographic and Limnological ResearchNational Institute of OceanographyHaifaIsrael
  2. 2.Institut für Physiologische Chemie, Abteilung Angewandte MolekularbiologieUniversität MainzMainzGermany

Bibliographic information

  • Book Title Invertebrate Immunology
  • Editors B. Rinkevich
    W.E.G. Müller
  • Series Title Progress in Molecular and Subcellular Biology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-59239-6
  • Softcover ISBN 978-3-642-79737-8
  • eBook ISBN 978-3-642-79735-4
  • Series ISSN 0079-6484
  • Edition Number 1
  • Number of Pages XIII, 250
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Immunology
    Biochemistry, general
    Cell Biology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


" essential text for any invertebrate immunologist. Furthermore, it should also be of interest to scientists with backgrounds in vertebrate immunology." Immunology Today