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Measles Virus

  • Volker ter Meulen
  • Martin A. Billeter

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 191)

Table of contents

  1. Front Matter
    Pages I-IX
  2. M. Katz
    Pages 1-12
  3. C. J. Clements, F. T. Cutts
    Pages 13-33
  4. S. M. Horikami, S. A. Moyer
    Pages 35-50
  5. B. K. Rima, J. A. P. Earle, K. Baczko, P. A. Rota, W. J. Bellini
    Pages 65-83
  6. P. Borrow, M. B. A. Oldstone
    Pages 85-100
  7. S. Schneider-Schaulies, J. Schneider-Schaulles, L. M. Dunster, V. Ter Meulen
    Pages 101-116
  8. R. S. Van Binnendijk, R. W. J. Van Der Heijden, A. D. M. E. Osterhaus
    Pages 135-148
  9. U. G. Liebert, D. Finke
    Pages 149-166
  10. E. Norrby
    Pages 167-180
  11. Back Matter
    Pages 193-198

About this book

Introduction

Measles, also called the greatest killer of children in history, still annually affects about 50 million individuals and causes close to a million deaths primarily in developing countries. Before the advent of measles vaccine some 30 years ago, these figures were roughly three times higher. Attenuated measles virus (MV) strains, all quite closely related to the original Edmonston isolate, have a very good record as a safe and highly efficacious vaccine and have brought down the measles toll in industrialized countries to almost negligible levels. However, recent outbreaks in the USA and Europe have again brought the measles problem to public attention. Sadly enough, these outbreaks were more instrumental in inducing activities to drastically reduce and hopefully finally eradicate measles than were the ten thousand times higher number of victims in developing countries. To reach this goal, as detailed in this volume, apparently it is not enough to of the existing vaccine as was the rigorously enforce use case with smallpox eradication: the intricacies of measles disease phenomena, in particular the generalized immune suppression which favors secondary infections, require more basic knowledge of the virus-host interactions and probably the development of new vaccines for special applications such as first immunizations of very young infants in developing countries.

Keywords

Immunologie Impfung Masern Masernvirologie und Immunologie Measles Measles vaccination biology childhood diseases immunology infection molecular biology vaccination virology virus

Editors and affiliations

  • Volker ter Meulen
    • 1
  • Martin A. Billeter
    • 2
  1. 1.Institut für Virologie und Immunbiologie der Universität WürzburgWürzburgGermany
  2. 2.Institut für Molekularbiologie IUniversität ZürichZürichSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-78621-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-78623-5
  • Online ISBN 978-3-642-78621-1
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site
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