The Pharmacology of Alcohol Abuse

  • Henry R. Kranzler

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 114)

Table of contents

  1. Front Matter
    Pages I-XXVI
  2. J. Moring, W. J. Shoemaker
    Pages 11-53
  3. M. K. Ticku, A. K. Mehta
    Pages 103-119
  4. J. R. Volpicelli, B. J. Berg, N. T. Watson
    Pages 169-184
  5. J. Littleton
    Pages 231-260
  6. R. F. Anton, H. C. Becker
    Pages 315-367
  7. R. K. Fuller, R. Z. Litten
    Pages 369-381
  8. H. Rommelspacher, C. Müller
    Pages 443-473
  9. B. F. Sands, C. M. Knapp, D. A. Ciraulo
    Pages 475-512
  10. H. R. Kranzler, A. T. McLellan, M. J. Bohn
    Pages 513-537
  11. Back Matter
    Pages 539-549

About this book


In recent years alcohol abuse has received increased international attention. Such attention is justified by the enormous negative impact that this disorder has on health, as well as on economic and social well-being. Governmental and other sources of research support have promoted substantial investigation into the negative consequences of alcohol, examining both animal models and human subjects. Consequently, there has been a virtual explosion of preclinical and clinical data, much of it focused on alcohol's pharmacologic effects. However, there have been few efforts to integrate this wealth of new information into a single, manageable volume. This volume provides an up-to-date, in-depth treatment of the phar­ macology of alcohol, particularly as it relates to alcohol abuse. The over­ riding theme of the book is the interplay between the preclinical and clinical domains. Increasingly, these areas of investigation have served to inform one another, a trend that can be expected to grow with time. The topics covered include the effects of alcohol on biological systems and the impact of medications on those effects. In addition, recent insights obtained from molecular biological investigations are discussed in terms of their relevance for understanding the effects of alcohol at the cellular level and the implica­ tions of these for the development of medications. Consideration is also given to important methodological issues that influence the evaluation of medications in the context of clinical trials.


Alcohol Pharmacology Alcoholism Treatment Alkoholismus Etiology of Alcoholism Neuropharmacology of Alcohol Pharmacotherapy of Alcoholism Sucht alcoholism biology ethanol molecular biology neuropharmacology pharmacology pharmacotherapy research

Editors and affiliations

  • Henry R. Kranzler
    • 1
  1. 1.Division of Addictive Disorders, Department of Psychiatry, MC2103University of Connecticut School of MedicineFarmingtonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-78437-8
  • Online ISBN 978-3-642-78435-4
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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