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  • © 1993

The HLA System in Clinical Transplantation

Basic Concepts and Importance

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Table of contents (33 chapters)

  1. Allorecognition of HLA Molecules

    1. Transplantation of the Alloimmunized Patient

      • E. Möller, S. Sumitran-Karuppan
      Pages 243-257
  2. HLA-Matching

    1. Front Matter

      Pages 259-259
    2. HLA Matching in Clinical Organ Transplantation

      • T. Leivestad, E. Vartdal, E. Thorsby
      Pages 261-269
    3. Transplantation Tolerance and Noninherited Maternal HLA Antigens

      • F. H. J. Claas, L. Zhang, J. J. van Rood
      Pages 270-276
    4. What To Do with the Immunized Patient. How to Avoid Humoral Immunization

      • P. Fauchald, D. Albrechtsen, A. V. Reisaeter, A. Jakobsen, B. G. Solheim
      Pages 277-283
  3. Immunosuppression

    1. Front Matter

      Pages 285-285
    2. Immunosuppressive Therapy

      • J.-F. Bach, J.-P Viard
      Pages 287-299
    3. Anti-idiotypic Antibodies in the HLA System

      • S. M. Mariani, E. A. Armandola, S. Ferrone
      Pages 317-324
  4. Rejection

    1. Front Matter

      Pages 325-325
    2. Cellular and Molecular Mechanism of Rejection and Role of Viral Infection

      • R. Renkonen, I. Lautenschlager, P. Häyry
      Pages 327-338
  5. Bone Marrow Transplantation

    1. Front Matter

      Pages 349-349
    2. Purging of Bone Marrow

      • G. Kvalheim
      Pages 373-380
  6. Xenografting

    1. Front Matter

      Pages 381-381
    2. Xenografting: Is It Feasible?

      • J. Buyske, H. Auchincloss Jr.
      Pages 383-391

About this book

With this book we· want to address young graduate students, clini­ cians involved in transplantation, and technicians in transplantation immunology laboratories. The volume should give a comprehensive but basic, up to date introduction to the structure, function, and clinical importance of the HLA system. We believe that there is a need for such a survey, and think that the present level of our knowledge is an optimal occasion for publication. A significant number of ques­ tions have now been resolved, and our knowledge has reached a level of sophistication that provides the basis for additional questions and answers. Although the emphasis of this book is on the role of HLA anti­ gens in clinical transplantation, their involvement in other clinical contexts is also discussed. The main focus is on the human MHC an­ tigenic system, but MHC systems in other species are described as they contribute to our understanding of the structural and functional characteristics of HLA antigens. Some important issues related to laboratory techniques are also covered. The contributors have a close affiliation to the field of transplan­ tation immunology. A majority have even been playing important roles in unraveling the HLA system and its functions. We believe this has contributed significantly to the quality and clinical and practical relevance of the book. As editors, we drew up the principal guidelines and took care that the chapters can be read as separate entities, although this invariably results in some overlapping.

Editors and Affiliations

  • Department Group for Laboratory Medicine, University of Oslo Rikshospitalet, Oslo, Norway

    Bjarte G. Solheim

  • Department of Microbiology and Immunology, New York Medical College, Valhalla, USA

    Soldano Ferrone

  • Department for Clinical Immunology, Huddinge sjukhus, Huddinge, Sweden

    Erna Möller

Bibliographic Information

  • Book Title: The HLA System in Clinical Transplantation

  • Book Subtitle: Basic Concepts and Importance

  • Editors: Bjarte G. Solheim, Soldano Ferrone, Erna Möller

  • DOI: https://doi.org/10.1007/978-3-642-77506-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1993

  • Softcover ISBN: 978-3-642-77508-6Published: 15 November 2011

  • eBook ISBN: 978-3-642-77506-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIX, 429

  • Topics: Allergology, Immunology, Surgery, Human Genetics, Oncology, Cell Biology

Buy it now

Buying options

Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access