Membrane Defenses Against Attack by Complement and Perforins

  • Charles J. Parker

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 178)

Table of contents

  1. Front Matter
    Pages i-vii
  2. A. Nicholson-Weller
    Pages 7-30
  3. G. D. Ross
    Pages 31-44
  4. M. K. Liszewski, J. P. Atkinson
    Pages 45-60
  5. M. H. Holguin, C. J. Parker
    Pages 61-85
  6. L. S. Zalman
    Pages 87-99
  7. W. F. Rosse
    Pages 163-173
  8. Back Matter
    Pages 185-190

About this book


In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.


Komplementsystem Zellmembran activation anemia cell cell membrane hämolytische lymphocytes membrane nächtliche paroxysmale protein proteins receptor regulation

Editors and affiliations

  • Charles J. Parker
    • 1
  1. 1.Department of Veterans Affairs Medical CenterUniversity of Utah School of MedicineSalt Lake CityUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1992
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-77016-6
  • Online ISBN 978-3-642-77014-2
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site
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