Pharmacology of Antihypertensive Therapeutics

  • Detlev Ganten
  • Patrick J. Mulrow

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 93 / 1)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. H. J. Kramer
    Pages 21-63
  3. J. Conway, A. Bilski
    Pages 65-104
  4. P. A. van Zwieten
    Pages 105-129
  5. G. Sponer, W. Bartsch, R. G. Hooper
    Pages 131-226
  6. W. Kobinger, L. Pichler
    Pages 227-262
  7. L. G. Howes, W. J. Louis
    Pages 263-285
  8. W. J. Louis, L. G. Howes
    Pages 287-299
  9. S. Kazda, A. Knorr
    Pages 301-375
  10. T. Unger, P. Gohlke, M.-G. Gruber
    Pages 377-481
  11. R. Henning, A. Wagner, B. A. Schölkens
    Pages 483-505
  12. G. Schröder, R. Gryglewski, J. Mehta, G. Stock
    Pages 507-531
  13. P. R. Saxena, W. Wouters
    Pages 533-558
  14. B.-G. Schulz, R. Casto, A. Jödicke, G. Stock
    Pages 559-595
  15. R. E. Lang
    Pages 597-642
  16. H. Becker
    Pages 709-739
  17. A. Zanchetti
    Pages 741-763
  18. D. A. Eichler, D. P. Clough
    Pages 783-807
  19. R. Lang, H. M. Steffen, W. Kaufmann, L. Wilhelmsen, J. I. S. Robertson, N. M. Kaplan et al.
    Pages 809-858
  20. V. F. Mauro
    Pages 859-899
  21. Back Matter
    Pages 901-922

About this book


The previous volume on Antihypertensive Agents in the Handbook of Experi­ mental Pharmacology, published in 1977, was edited by the late Franz Gross from the Department of Pharmacology in Heidelberg, who was one of the grand old men in hypertension research. Now, more than 10 years later, it is necessary to update this volume. From the early days of antihypertensive drug treatment, starting about 30 years ago with drugs such as reserpine and guanethidine, the pharmacology of cardiovas"­ cular therapy has evolved into a highly sophisticated and effective therapeutic regimen. The major breakthroughs in the 1960s were the introduction of diuretics and beta-blockers. Then, in the 1980s, came the calcium antagonists and con­ verting enzyme inhibitors. It can be anticipated that the next decade will see a further expansion and sophistication of blood pressure lowering drugs. This book provides a state-of-the-art discussion of chemical, experimental, and clinical pharmacological data as well as of practical experience with drugs which are presently being used or which are going to be introduced on the market in the near future. The purpose of this volume is to provide a complete discussion of antihypertensive agents. Each major class of antihypertensive drugs is treated exhaustively in a separate chapter, fully referenced with chemical formulae, and richly illustrated with figures and tables. International authorities were asked to contribute in their respective fields of expertise.


Antihypertonikum Hypertonie Hämodynamik drug drug development hypertonia pharmacology toxicity

Editors and affiliations

  • Detlev Ganten
    • 1
  • Patrick J. Mulrow
    • 2
  1. 1.German Institute for High Blood Pressure Research and Department of PharmacologyUniversity of HeidelbergHeidelbergGermany
  2. 2.Medical College of OhioToledoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74211-8
  • Online ISBN 978-3-642-74209-5
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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