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Organtransplantation in Rats and Mice

Microsurgical Techniques and Immunological Principles

  • Book
  • © 1998

Overview

Editors:
  1. Wolfgang Timmermann

    1. Chirurgische Universitätsklinik und Poliklinik Würzburg, Würzburg, Germany

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  2. Heinz-Jochen Gassel

    1. Chirurgische Universitätsklinik und Poliklinik Würzburg, Würzburg, Germany

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  3. Karin Ulrichs

    1. Chirurgische Universitätsklinik und Poliklinik Würzburg, Würzburg, Germany

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  4. Robert Zhong

    1. Department of Surgery, University of Western Ontario, London, Canada

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  5. Arnulf Thiede

    1. Chirurgische Universitätsklinik und Poliklinik Würzburg, Würzburg, Germany

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  • Description and discussion of rat and mouse models for organ transplantation

  • Practical and theoretical aspects

  • Short and concise chapters

  • Most recent developments in the field

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Table of contents (68 chapters)

  1. Basic Microsurgical Techniques for Rat Organ Transplantation

    1. Combined Abdominal Organ Transplantation

      • D. Meyer, H.-J. Gassel
      Pages 141-147

  2. Basic Microsurgical Techniques for Mouse Organ Transplantation

    1. Front Matter

      Pages 149-149
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    2. Surgical Technique for Skin Transplantation in Mice

      • R. Kellersmann, R. Zhong
      Pages 151-154

    3. Surgical Technique for Vascularized Ear Transplantation in Mice

      • J. Jiang, A. Humar, R. Zhong
      Pages 155-160

    4. A Microsurgical Technique for Orthotopic Aorta Transplantation in Mice

      • J. Jiang, Z. Zhang, L. Chow, R. Zhong
      Pages 161-165

    5. Pancreatic Islet and Proislet Transplantation in the Mouse Model

      • C. J. Simeonovic, J. C. Zarb, L. S. Gazda, K. J. Lafferty, J. D. Wilson
      Pages 167-177

    6. Vascular Thymus Transplantation in Mice

      • J. Jiang, H. Wang, Q. Madrenas, R. Zhong
      Pages 179-184

    7. Surgical Techniques for Mouse Heart Transplantation

      • Z. K. Chen, S. Metcalfe
      Pages 185-192

    8. Microsurgical Techniques for Kidney Transplantation in Mice

      • Z. Zhang, R. Zhong
      Pages 193-201

    9. Microsurgical Techniques for Small Bowel Transplantation in Mice

      • Z. Zhang, D. Grant, R. Zhong
      Pages 203-211

    10. Surgical Techniques for Orthotopic Liver Transplantation in Mice

      • S. Qian, F. Fu, W. Li, J. J. Fung
      Pages 213-221

  3. Immunological Concepts and Techniques

    1. Front Matter

      Pages 223-223
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    2. Concepts and Mechanisms of Immune Activation, Graft Rejection, Immunosuppression, and Tolerance

      • W. Müller-Ruchholtz
      Pages 225-252

    3. Immunogenetic Basis of Organ Graft Rejection in Rat and Mouse

      • E. Günther
      Pages 253-276

    4. Oral Feeding and Intrathymic Injection of MHC Class I-derived Allopeptides Prolong Graft Survival

      • N. Zavazava, K.-A. Y. Ott, F. Fändrich
      Pages 277-284

    5. Microchimerism in Organ Transplantation

      • H. J. Schlitt, S. Ko, A. Deiwick, J. Hundrieser
      Pages 285-298

    6. Gene Transfer and Tolerance Induction

      • W. Wong, J. Fry, K. Hyde, P. Morris, K. Wood
      Pages 299-312

    7. Lessons from Knockout and Transgenic Mice

      • H. Wang, P. F. Halloran
      Pages 313-324

    8. Immunological Methods in Small Animal Research

      • C. Otto, M. Gasser, K. Ulrichs
      Pages 325-337

    9. Analytical Methods in Molecular Biology

      • U. Beutner, K. Ulrichs
      Pages 339-350
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Keywords

About this book

Main focus of the new book will be the description and discussion of rat and mouse models for organ transplantation. Various microsurgical techniques will be presented which allow transplantation of functional organs in syngeneic systems. In particular, the extremely difficult methods necessary for organ transplantation in mice will be presented and evaluated. Besides these practical aspects the book will also cover the theoretical sides of organ transplantation like the immunobiology of allotransplantation. Special emphasis will be given to the resurgent field of xenotransplantation. The results from xenograft models developed in the recent years using rats or mice will be reviewed and their impact on future human xenotransplantation will be discussed.

Editors and Affiliations

  • Chirurgische Universitätsklinik und Poliklinik Würzburg, Würzburg, Germany

    Wolfgang Timmermann, Heinz-Jochen Gassel, Karin Ulrichs, Arnulf Thiede

  • Department of Surgery, University of Western Ontario, London, Canada

    Robert Zhong

Bibliographic Information

  • Book Title: Organtransplantation in Rats and Mice

  • Book Subtitle: Microsurgical Techniques and Immunological Principles

  • Editors: Wolfgang Timmermann, Heinz-Jochen Gassel, Karin Ulrichs, Robert Zhong, Arnulf Thiede

  • DOI: https://doi.org/10.1007/978-3-642-72140-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Softcover ISBN: 978-3-642-72142-7Published: 22 December 2011

  • eBook ISBN: 978-3-642-72140-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXIII, 671

  • Topics: General Surgery, Transplant Surgery

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

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