© 1987


Biology and Immunotherapy

  • Michael B. A. Oldstone
Conference proceedings

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 134)

Table of contents

  1. Front Matter
    Pages i-vii
  2. M. B. A. Oldstone
    Pages 1-4
  3. C. J. Peters, P. B. Jahrling, C. T. Liu, R. H. Kenyon, K. T. McKee Jr., J. G. Barrera Oro
    Pages 5-68
  4. J. B. McCormick
    Pages 69-78
  5. M. C. Weissenbacher, R. P. Laguens, C. E. Coto
    Pages 79-116
  6. C. R. Howard
    Pages 117-130
  7. M. B. A. Oldstone
    Pages 211-229
  8. S. P. Fisher-Hoch, J. B. McCormick
    Pages 231-239
  9. Back Matter
    Pages 241-242

About these proceedings


M. B. A. OLDSTONE Viruses are generally studied either because they cause significant human, animal or plant disease or for their utility as materials to probe a basic phenomenon in biology, chemistry, genetics or molecular biology. Arenaviruses are unusually interesting in that they occupy both of these categories. Arenaviruses cause severe human diseases known primarily as the hemor­ rhagic fevers occurring in South and Latin America (Bolivia: Machupo virus and Argentina: Junin virus) and in Africa (Lassa virus). Because such viruses produce profound disability and may kill the persons they infect, they are a source of economic hardship in the countries where they are prevalent. Further, they provide new problems for health care personnel owing to the narrowing of the world as visitors from many countries increasingly travel to and from these endemic areas. In addition, lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling than those elicited by other arenaviruses. Yet LCMV is likely of greater concern to non-arena-virologists and experimentalists using tissue culture or animals, i. e. , workers in molecular biology, cancer research, virology, immunobiology, etc. , because normal appearing cultured cells or tissues and animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and transmit that infection to laboratory workers (reviewed OLDSTONE and PETERS 1978). For example, HINMAN et al.


diseases genetics immunobiology immunotherapy infection molecular biology pathology virology virus

Editors and affiliations

  • Michael B. A. Oldstone
    • 1
  1. 1.Department of ImmunologyScripps Clinic and Research FoundationLa JollaUSA

Bibliographic information

  • Book Title Arenaviruses
  • Book Subtitle Biology and Immunotherapy
  • Editors Michael B.A. Oldstone
  • Series Title Current Topics in Microbiology and Immunology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1987
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-17322-9
  • Softcover ISBN 978-3-642-71728-4
  • eBook ISBN 978-3-642-71726-0
  • Series ISSN 0070-217X
  • Edition Number 1
  • Number of Pages VII, 242
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Medical Microbiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Consumer Packaged Goods