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Drugs Affecting Lipid Metabolism

  • Rodolfo Paoletti
  • David Kritchevsky
  • William L. Holmes

Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Table of contents

  1. Front Matter
    Pages I-XVI
  2. M. D. Siperstein, H. DoVale, J. R. Silber
    Pages 1-8
  3. R. A. Parker, S. J. Miller, D. M. Gibson
    Pages 9-13
  4. K. A. Mitropoulos
    Pages 14-20
  5. A. M. Gotto, W. A. Bradley, L. Chan, S. H. Gianturco, H. J. Pownall, J. T. Sparrow et al.
    Pages 52-55
  6. C. C. Shoulders, M. J. Ball, J. I. Mann, F. E. Baralle
    Pages 56-58
  7. G. Ghiselli, J. Heibig, F. Turturro, A. M. Gotto Jr., E. Wittels
    Pages 63-68
  8. P. Nilsson-Ehle
    Pages 83-87
  9. Th. Olivecrona, S. R. Price, P. H. Pekala, R. O. Scow, S. S. Chernick, H. Semb et al.
    Pages 88-93
  10. R. M. Gaion, P. Dorigo
    Pages 94-97
  11. J. H. Veerkamp, R. J. A. Paulussen
    Pages 98-104
  12. R. W. Wissler, D. Vesselinovitch
    Pages 111-116
  13. A. C. Beynen, A. G. Lemmens, J. F. C. Glatz, M. B. Katan, L. F. M. Van Zutphen
    Pages 122-125
  14. S. Fantappié, E. Bosisio, M. Crestani, G. Galli, A. L. Catapano
    Pages 126-130
  15. M. R. Lovati, L. Allievi, C. Manzoni, C. Galli, C. R. Sirtori
    Pages 131-135
  16. C. R. Sirtori, A. Bondioli
    Pages 142-149
  17. D. B. Hunninghake, D. M. Hibbard, W. C. Duane, M. L. Freeman, W. F. Prigge, K. J. Graham et al.
    Pages 150-154
  18. B. E. Phillipson, W. E. Connor, W. S. Harris, D. R. Illingworth
    Pages 155-157
  19. C. Galli, C. Mosconi, L. Medini, E. Tremoli
    Pages 162-166
  20. C. R. Sirtori, A. Canavesi, C. Manzoni, M. R. Lovati
    Pages 174-180
  21. D. Kritchevsky
    Pages 197-199
  22. D. Crook, I. F. Godsland, J. C. Montgomery, V. Wynn
    Pages 215-218
  23. D. A. White, G. D. Bell, F. Cacciaguerra, B. Middleton
    Pages 223-226
  24. M.-R. Taskinen, E. A. Nikkilä
    Pages 231-235
  25. H. B. Brewer Jr., R. E. Gregg, S. W. Law, J. M. Hoeg, L. A. Zech
    Pages 236-243
  26. P. J. Barter, G. J. Hopkins
    Pages 244-246
  27. H. Y. Pan, D. A. Willard, P. T. Funke, D. N. McKinstry
    Pages 255-259
  28. H. Mabuchi, N. Kamon, H. Fujita, I. Michishita, M. Takeda, K. Kajinami et al.
    Pages 260-268

About these proceedings

Introduction

The recent symposium and the appearance of this new book on Drugs Affecting Lipid Metabolism take place at a very unusual time for the development of this area. After the publication and wide acceptance of the results of the cholestyramine study by the Lipid Clinics in the USA, showing for the first time a direct association between drug induced reduction of plasma levels of total and LDL cholesterol and coronary heart disease in a high risk population, an unparalleled interest in drugs and other procedures able to control plasma cholesterol levels has been activated. Two other significant events occurred during 1986 and 1987: the availability of compact instruments for the immediate determination of total cholesterol in plasma or total blood and the developments of new agents such as the inhibitors of HMG-CoA (hydroxymethyl­ glutaryl CoA) reductase and ACAT inhibitors, with potentially great effect on plasma lipid levels after oral administration. These new advances, together with the combined efforts of cell biologists and lipoprotein chemists, have set the pace for an exciting period of research and clinical applications of diets and drugs af­ fecting lipids. This volume, which includes the work of many of the leading world laboratories, represents an authoritative and up-to-date ap­ praisal of the status of the art and a stimulus to future research at laboratory and clinical level in an area of opportunity for clinical and preventive medicine.

Keywords

Lipid Lipoprotein development drug lipide metabolism protein research

Editors and affiliations

  • Rodolfo Paoletti
    • 1
  • David Kritchevsky
    • 2
  • William L. Holmes
    • 3
  1. 1.School of PharmacyUniversity of MilanMilanItaly
  2. 2.The Wistar InstitutePhiladelphiaUSA
  3. 3.West ChesterUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-71702-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1987
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-71704-8
  • Online ISBN 978-3-642-71702-4
  • Series Print ISSN 0172-6625
  • Buy this book on publisher's site
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