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Metabolic Control in Diabetes Mellitus Beta Adrenoceptor Blocking Drugs NMR Analysis of Cancer Cells Immunoassay in the Clinical Laboratory Cyclosporine

  • Authors
  • W. Berger
  • R. Flückiger
  • H. G. Köppe
  • K. T. Holmes
  • C. E. Mountford
  • E. L. Nickoloff
  • T. G. Payne
  • M. H. Schreier
  • I. C. P. Smith
  • R. M. Wenger

Part of the Progress in Clinical Biochemistry and Medicine book series (PCBM, volume 3)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Carolyn E. Mountford, Kerry T. Holmes, Ian C. P. Smith
    Pages 73-112
  3. Eileen L. Nickoloff
    Pages 113-155
  4. Roland M. Wenger, Trevor G. Payne, Max H. Schreier
    Pages 157-191
  5. Back Matter
    Pages 192-192

About these proceedings

Introduction

The close association between blood glucose control and the well-being of the patient, as well as the risk for the development of the "late" complications of 3 diabetes, make it necessary to attain near normalisation of blood glucosel- ). Signifi­ cant progress has been made in this direction in the last few years because of the advancement of analytical techniques for the monitoring of both metabolic status and the functional state of the pancreas and the kidneys, organs involved in the disease process. The respective methodologies are the test strips for self-monitoring of glucose in blood and urine, the measurement of the nonenzymatic glycosylation of hemoglobin and serum proteins, the C-peptide assay, and the determination of small amounts of albumin in urine. The test strip methodology for determination of glucose in blood and urine has made possible home blood glucose monitoring which enables the patient to aim for treatment targets near the physiological range. To this information on short term glycemia obtained by the patient, the determination of hemoglobin glycosylation in the clinical chemistry laboratory adds quantitative information about averaged long­ term glycemic control. The C-peptide assay allows evaluation of the residual pancreatic function in the presence of exogenous insulin. Results of a C-peptide assay are helpful in selecting the appropriate treatment for poorly controlled maturity-onset diabetes. The detection of microalbuminuria, an abnormal albumin excretion below the level of "Albustix" detection, establishes nephropathy before renal damage becomes irreversible.

Keywords

Diabetes Diabetes mellitus Insulin Pancreas chemistry metabolic control nuclear magnetic resonance (NMR) protein proteins

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-70998-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-71000-1
  • Online ISBN 978-3-642-70998-2
  • Series Print ISSN 0177-8757
  • Buy this book on publisher's site
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