© 1984

Radiocontrast Agents

  • Milos Sovak

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 73)

Table of contents

  1. Front Matter
    Pages I-XVI
  2. G. B. Hoey, K. R. Smith
    Pages 23-125
  3. C. B. Higgins
    Pages 193-251
  4. M. Sovak, C. B. Higgins
    Pages 253-294
  5. M. Sovak
    Pages 463-477
  6. P. B. Dean, D. B. Plewes
    Pages 479-523
  7. J. A. Nelson
    Pages 533-542
  8. M. R. Violante, H. W. Fischer
    Pages 543-576
  9. Back Matter
    Pages 589-612

About this book


Contrast media are drugs by default. Had there been no default, there would be no need for a related pharmacology, and thus no need for this book. Radiographic contrast media (CM) are substances whose primary purpose is to enhance diagnostic information of medical imaging systems. The position of CM in pharmacology is unique. First, there is the unusual requirement of biological inertness. An ideal CM should be completely biologically inert, i.e., stable, not pharmacologically active, and efficiently and innocuously excretable. Because they fail to meet these requirements, CM must be considered drugs. The second unusual aspect of CM is that they are used in large quantities, their annual production being measured in tens of tons. It is not in spite of, but because of, the increased use of new radiographic systems, computed tomography, digital radiography, etc., that consumption is on the rise. And, it is not likely that the other emerging imaging modalities - NMR, ultrasonography, etc. - will displace radiographic CM soon; it is quite probable that these remarkable compounds will continue to play an active role in diagnostic imaging in the foreseeable future.


agents computed tomography (CT) diagnostic imaging medical imaging pharmacology tomography ultrasonography

Editors and affiliations

  • Milos Sovak
    • 1
    • 2
  1. 1.School of Medicine, Department of Radiology, S-009University of California in San DiegoLa JollaUSA
  2. 2.Biophysica FoundationLa JollaUSA

Bibliographic information

  • Book Title Radiocontrast Agents
  • Editors M. Sovak
  • Series Title Handbook of Experimental Pharmacology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1984
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-13107-6
  • Softcover ISBN 978-3-642-69517-9
  • eBook ISBN 978-3-642-69515-5
  • Series ISSN 0171-2004
  • Series E-ISSN 1865-0325
  • Edition Number 1
  • Number of Pages XVI, 612
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
    Imaging / Radiology
  • Buy this book on publisher's site
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