Pharmacology of the Eye

  • Marvin L. Sears

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 69)

Table of contents

  1. Front Matter
    Pages I-XXV
  2. M.-H. Heinemann
    Pages 1-17
  3. D. M. Maurice, S. Mishima
    Pages 19-116
  4. H. Shichi
    Pages 117-148
  5. P. L. Kaufman, T. Wiedman, J. R. Robinson
    Pages 149-191
  6. V. J. Lotti, J. C. LeDouarec, C. A. Stone
    Pages 249-277
  7. J. Stjernschantz
    Pages 311-365
  8. G. J. Chader
    Pages 367-384
  9. I. H. Leopold
    Pages 385-457
  10. J. R. Polansky, R. N. Weinreb
    Pages 459-538
  11. P. H. Fischer, W. H. Prusoff
    Pages 553-583
  12. I. Gery, R. B. Nussenblatt
    Pages 585-609
  13. R. W. Flower, M. O. Hall
    Pages 627-638
  14. A. M. Potts
    Pages 639-653
  15. A. M. Potts
    Pages 655-666
  16. T. R. Jones, T. W. Reid
    Pages 667-685
  17. D. Seigel
    Pages 687-697
  18. M. Rosenberg, L. M. Jampol
    Pages 715-720
  19. Back Matter
    Pages 721-738

About this book


Roots of the theory and practice of ocular pharmacology may be traced to the ancient Mesopotamian code of Hammurabi and then to several papyri reflecting the clinical interests of the Egyptians. The evolution of its art and science was irregularly paced until the nineteenth century when Kohler, in 1884, proved the anesthetic effect of cocaine on the cornea, and when Fraser, Laquer, Schmiedeberg, Meyer, and others studied the pharmacology of the autonomic nervous system by way of observations of the pupil. Advances in the past few decades have been nothing short of explosive. How can the student, physician, or basic research scientist stay in touch with these electrifying studies? To help with the answer to this question, the authors set as their goal the development of increased understanding so that the student, research scientist, and ophthalmologist can cope with the latest discoveries. The authors want to narrow what appears to be an ever-increasing gap between basic science and ophthalmology. The basic aspects of pharmacology have been presented in light of the natural physiology. In this regard, while distinctions among endogenous mechanisms, drug effects, and the pathogenesis of disease are to be separately recognized, appreciation must be given to the concept that both the desirable and unwanted manifestations or functions caused by either disease or drugs must very often represent a quantitative change in normal metabolic pathways.


Ophthalmikum cocaine drug eye pathogenesis pharmacology physiology research

Editors and affiliations

  • Marvin L. Sears
    • 1
  1. 1.Department of Ophthalmology and Visual Science, School of MedicineYale UniversityNew HavenUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1984
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-69224-6
  • Online ISBN 978-3-642-69222-2
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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