© 1977


The Role of Proteinases, and Blockage of Implantation by Proteinase Inhibitors


Table of contents

  1. Front Matter
    Pages 1-7
  2. Hans-Werner Denker
    Pages 8-9
  3. Hans-Werner Denker
    Pages 9-15
  4. Hans-Werner Denker
    Pages 15-75
  5. Hans-Werner Denker
    Pages 75-101
  6. Hans-Werner Denker
    Pages 101-104
  7. Back Matter
    Pages 105-124

About this book


The establishment of the morphologically and physiologically intimate contact be­ tween two genetically different individuals, mother and embryo, which takes place during implantation, has always exerted a fascination on researchers in biology and medicine. Recent years have also seen the beginnings of a more practice-oriented med­ ical interest in this event, as certain methods of contraception whose use is ever in­ creasing, namely intra-uterine devices (IUDs) and post-coital oral contraceptives, are based on it. On one hand, we have fairly well substantiated experimental and clinical evidence that the efficacy of these contraceptives lies with other factors as well, for example their influence on sperm migration and capacitation or their influence on the transportation of the unfertilized egg. On the other hand there appears to be more im­ portance in their influence on the blastocyst and on the early stages of implantation (Carol et aI. , 1973; Duncan and Wheeler, 1975; Hafez and Evans, 1973; Oettel, 1975). These stages in development are characterized by complex interactions between em­ bryo and mother, which have only lately been more exhaustively investigated and which are still subjects of intense research (Beier, 1973, 1974a; Blandau, 1971a; Finn and Porter, 1975; Hafez and Evans, 1973; Steven, 1975). It is expected that insight in­ to the mechanism of the action of postcoital contraceptives and a possible basis for the development of new concepts in contraception can be gained here.


Implantation animals biochemistry biology chemistry development embryo enzyme influence migration morphology protein regulation

Authors and affiliations

  1. 1.Abteilung Anatomie der Medizinischen FakultätRWTH AachenAachenFederal Republic of Germany

Bibliographic information

  • Book Title Implantation
  • Book Subtitle The Role of Proteinases, and Blockage of Implantation by Proteinase Inhibitors
  • Authors H.-W. Denker
  • Series Title Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d’anatomie et de morphologie expérimentale
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1977
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-540-08479-2
  • eBook ISBN 978-3-642-66781-7
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages , 123
  • Number of Illustrations 25 b/w illustrations, 0 illustrations in colour
  • Additional Information Title of the German original edition: Mechanismen der Implantation des Säugetierembryos und ihre experimentelle Beeinflussung
  • Topics Embryology
    Biomedicine, general
  • Buy this book on publisher's site