© 1977


Ultrastructure of Normal and Cryptorchid Testis Development


Table of contents

  1. Front Matter
    Pages N1-6
  2. Faruk Hadžiselimović
    Pages 7-7
  3. Faruk Hadžiselimović
    Pages 8-8
  4. Faruk Hadžiselimović
    Pages 9-10
  5. Faruk Hadžiselimović
    Pages 10-47
  6. Faruk Hadžiselimović
    Pages 47-59
  7. Faruk Hadžiselimović
    Pages 59-62
  8. Faruk Hadžiselimović
    Pages 62-63
  9. Faruk Hadžiselimović
    Pages 64-65
  10. Back Matter
    Pages 66-72

About this book


Cytological techniques have greatly improved in the last twenty years, largely as a result of further development of the microscope. Electron microscopy, in particular, has opened up great prospects for the study of cell morphology, while the develop­ ment of radio-immuno-assay has brought great progress in endocrinology. The applica­ tion of these two techniques, which are complementary to each other and provide mutually supporting evidence, is the subject of this monograph. The work is divided into two parts. The first deals with the ultrastructure of normal testicular development, describing four main elements of the testicle - the germ cells, the Sertoli cells, the peri tubular connective tissue and the Leydig cell- with details of their individual development. To make the electron micrographs more easily understandable, diagrams have been used to explain the most important points. The second part deals with cryptorchid testicles, including the primary and sec­ ondary changes involved and morphometric studies of the secondary changes. The significance of these ultrastructural observations for the treatment of cryptorchidism is emphasized. With the aid of radio-immuno-assay the level of testosterone in cryp­ torchid mice was determined and comparisons drawn between the ultrastructural changes in cryptorchidism in mouse and man. The experimental studies served as a basis for the hypothesis that, in all probability, a congenital disturbance of the hy­ pothalamo-hypophyso-gonadal axis is responsible for cryptorchidism. I hope that this monograph will contribute towards a better understanding of normal and cryptorchid testicular development and of the etiology of cryptorchidism.


biopsy cell development electron microscopy endocrinology microscopy morphology testis tissue

Authors and affiliations

  1. 1.Basler KinderspitalBasleSwitzerland

Bibliographic information

  • Book Title Cryptorchidism
  • Book Subtitle Ultrastructure of Normal and Cryptorchid Testis Development
  • Authors F. Hadziselimovic
  • Series Title Advances in Anatomy, Embryology and Cell Biology / Ergebnisse der Anatomie und Entwicklungsgeschichte / Revues d’anatomie et de morphologie expérimentale
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1977
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-540-08361-0
  • eBook ISBN 978-3-642-66715-2
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages , 72
  • Number of Illustrations 23 b/w illustrations, 0 illustrations in colour
  • Topics Urology
    Biomedicine, general
    Life Sciences, general
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals