Fundamental Aspects of Neoplasia

  • A. Arthur Gottlieb
  • Otto J. Plescia
  • David H. L. Bishop

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Biology of Tumor Viruses

    1. Front Matter
      Pages 1-1
    2. R. E. Benveniste, C. J. Sherr, M. M. Lieber, R. Callahan, G. J. Todaro
      Pages 29-53
    3. D. H. Moore
      Pages 55-59
    4. J. Schlom, D. Colcher, R. Michalides, G. Schochetman, J. Young, S. Spiegelman et al.
      Pages 61-78
  3. Tumor Immunology

  4. Clinical Aspects

    1. Front Matter
      Pages 153-153
    2. D. L. Morton, S. H. Golub, H. L. Sulit, R. K. Gupta, F. R. Eilber, E. C. Holmes et al.
      Pages 181-201
    3. E. E. Fraley, A. Y. Elliott, A. E. Castro, P. H. Cleveland, D. L. Bronson, T. R. Hakala et al.
      Pages 213-228
  5. DNA Polymerases of Malignant Cells and Associated Viruses

    1. Front Matter
      Pages 233-233
    2. L. A. Loeb, N. Battula, C. F. Springgate, G. Seal
      Pages 243-255
    3. A. A. Gottlieb, A. H. Smith, O. J. Plescia, D. E. Nicholson, S. Bowers, E. Pankuch et al.
      Pages 269-277
  6. Viral Expression and Cell Transformation

    1. Front Matter
      Pages 279-279
    2. M. Jacquet, Y. Groner, G. Monroy, J. Hurwitz
      Pages 281-291
    3. M. Green, S. Salzberg, M. S. Robin, M. C. Loni, S. Bhaduri, G. Shanmugam
      Pages 293-301
    4. J. P. Bader, D. J. Marciani
      Pages 303-313
  7. Tumor Cell Growth and Regulation

    1. Front Matter
      Pages 355-355
    2. R. J. Mannino Jr., M. M. Burger
      Pages 365-374
    3. A. M. Mauer, S. B. Murphy
      Pages 389-399
    4. J. Folkman, M. Klagsbrun
      Pages 401-412
    5. Lewis Thomas
      Pages 413-421
  8. Back Matter
    Pages 422-424

About this book


The control of cancer is at once a major public health problem and a problem of fundamental biologic interest. As a result of technologic developments and new insights in the realm of molecular biology, new and important approaches to an understanding of neoplasia are now possible. Several aspects of neoplasia are clearly of microbiologic interest, including the role of viruses in the etiology of cancer, control of the immune response to tumor cells, and the susceptibility of tumor-bearing hosts to overwhelming infection as a result of immuno­ deficiency. Recent advances in these areas led us to organize this symposium, and, through this publication, to record some of the progress being made in laboratories around the world in understanding some of the basic aspects of the cancer problem. This symposium was held as part of the commemoration of the twentieth anniversary of the Waksman Institute of Microbiology. Dr. Waksman's devo­ tion to the study of the smallest forms of life and the commitment of the Waksman Institute to the free pursuit of knowledge are the underpinnings of the institute's research eHorts in the broad area of microbiology, including the problem of neoplasia. It is of interest to note that actinomycin, one of the earliest antibiotics discovered in Waksman's laboratory, was also one of the first compounds found to be clinically useful in the treatment of certain types of cancer.


Immunologie Immunotherapie Krebs Viruskrankheit antibiotics cancer infection molecular biology therapy tumor

Editors and affiliations

  • A. Arthur Gottlieb
    • 1
  • Otto J. Plescia
    • 2
  • David H. L. Bishop
    • 3
  1. 1.Department of Microbiology and ImmunologyTulane University School of MedicineNew OrleansUSA
  2. 2.Institute of MicrobiologyRutgers UniversityNew BrunswickUSA
  3. 3.The Medical CenterUniversity of AlabamaBirminghamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1975
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-66114-3
  • Online ISBN 978-3-642-66112-9
  • Buy this book on publisher's site
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