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Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung

  • W. Arber
  • R. Haas
  • W. Henle
  • P. H. Hofschneider
  • N. K. Jerne
  • P. Koldovský
  • H. Koprowski
  • O. Maaløe
  • R. Rott
  • H. G. Schweiger
  • M. Sela
  • L. Syruček
  • P. K. Vogt
  • E. Wecker
Conference proceedings

Table of contents

  1. Front Matter
    Pages i-iii
  2. F. Lacour, E. Nahon-Merlin, M. Michelson
    Pages 1-39
  3. T. A. Trautner, H. Ch. Spatz
    Pages 61-88
  4. Back Matter
    Pages 139-175

About these proceedings

Introduction

General aspects of nucleic acid uptake by mammalian cells have been the subject of several reviews during the last few years (PAGANO, 1970; BHARGAVA and SHANMUGAM, 1971; DUBES, 1971; RYSER, 1967). These reviews covered methods used for the infection of cells by viral nucleic acids as well as interaction of mammalian cells with non-viral nucleic acids. This article is restricted to a discussion of experiments with poliovirus RNA and focuses special attention on the steps following the uptake of RNA into a cell, aspects that were not discussed in earlier review articles. The fate of input RNA once inside the cell is determined by the host cell but experimental conditions can be chosen to favor the survival of input RNA and the induction of a virus growth cycle by interfering with host-cell meta­ bolism through events that, in the case of infection with intact virus, might be controlled by viral proteins.

Keywords

Immunität RNA biology cell growth immunology infection microbiology protein proteins virus

Editors and affiliations

  • W. Arber
    • 1
  • R. Haas
    • 2
  • W. Henle
    • 3
  • P. H. Hofschneider
    • 4
  • N. K. Jerne
    • 1
  • P. Koldovský
    • 3
  • H. Koprowski
    • 3
  • O. Maaløe
    • 5
  • R. Rott
    • 6
  • H. G. Schweiger
    • 7
  • M. Sela
    • 8
  • L. Syruček
    • 9
  • P. K. Vogt
    • 10
  • E. Wecker
    • 11
  1. 1.BasleSwitzerland
  2. 2.FreiburgGermany
  3. 3.PhiladelphiaUSA
  4. 4.MartinsriedGermany
  5. 5.CopenhagenDenmark
  6. 6.GießenGermany
  7. 7.WilhelmshavenGermany
  8. 8.RehovotIsrael
  9. 9.PragueCzech Republic
  10. 10.SeattleUSA
  11. 11.WürzburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-65772-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 1973
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-65774-0
  • Online ISBN 978-3-642-65772-6
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site
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