© 1972

Steroids and Brain Edema

  • H. J. Reulen
  • K. Schürmann

Table of contents

  1. Front Matter
    Pages I-XII
  2. Experimental Aspects of Brain Edema and Therapeutic Approach

    1. Maria Spatz, Zbigniew M. Rap, Stanley I. Rapoport, Igor Klatzo
      Pages 19-27
    2. Harry B. Demopoulos, Paul Milvy, Sophia Kakari, Joseph Ransohoff
      Pages 29-39
  3. Effects of Steroids on Experimental Brain Edema

    1. Hanna M. Pappius
      Pages 57-63
    2. Don M. Long, Robert E. Maxwell, Lyle A. French
      Pages 65-76
    3. Don M. Long, Robert E. Maxwell, Kil Soo Choi, Harry O. Cole, Lyle A. French
      Pages 87-94
    4. Charles B. Wilson, Marvin Barker, Takao Hoshino, Anthony Oliver, Robert Downie
      Pages 95-100
    5. Marcial G. Lewin, Hanna M. Pappius, Robert R. Hansebout
      Pages 101-112
    6. Barry A. Siegel, Rebecca K. Studer, E. James Potchen
      Pages 113-121
    7. S. Shibata, J. W. Norris, C. P. Hodge, H. M. Pappius
      Pages 123-125
    8. Daniel Bartko, Hans J. Reulen, Herrmann Koch, Kurt Schürmann
      Pages 127-137
  4. Mechanisms of Action of Steroids on Brain Edema

    1. Robert R. Hansebout, Marcial G. Lewin, Hanna M. Pappius
      Pages 153-155
    2. Raymond A. Clasen, Walid A. Hindo, Sylvia Pandolfi, Iris Laing
      Pages 157-166
    3. Bienvenido D. Ortega, Harry B. Demopoulos, Joseph Ransohoff
      Pages 167-175

About this book


The control of brain edema is still one of the major problems in surgical and conservative treatment of various cerebral lesions. Many attempts have been made to develop methods for reducing the high mortality associated with brain edema. Mter many years of using hypertonic solutions it can be stated that this type of therapy has not yielded satisfactory results. During recent years increasing evidence has been accumulated on the efficacy of steroids on brain edema. Steroids were reported to result in rapid relief of signs and symptoms of increased intracranial pressure and neurological dysfunction accompanying cerebral edema. It was the aim of this workshop to evaluate the effect of corticosteroids on brain edema as an advance in therapy. It was hoped that this could be achieved by a multi­ disciplinary approach. Though, the volume contains the contributions of various experts - internists, neurochemists, neurologists, neuropathologists, neurosurgeons, pharmacologists, physiologists - who have added considerable experimental and clin­ ical evidence on the action of steroids on brain edema. New pathophysiological aspects regarding the mechanisms underlying the formation and resolution of brain The effectiveness of corticosteroid therapy in various forms edema are presented. of clinical and experimental brain edema, e. g. accompanying brain tumors, head injury, spinal cord injury, cerebrovascular lesions, etc. as well as dosage and duration of treatment are critically discussed.


brain brain tumor central nervous system cerebral ischemia growth head head injury inflammation mortality nervous system neurosurgery physiology spinal cord surgery therapy

Editors and affiliations

  • H. J. Reulen
    • 1
  • K. Schürmann
    • 1
  1. 1.Neurochirurgische Universitätsklinik MainzMainzW. Germany

Bibliographic information

  • Book Title Steroids and Brain Edema
  • Editors Hans J. Reulen
    Kurt Schürmann
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1972
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-540-05958-5
  • eBook ISBN 978-3-642-65448-0
  • Edition Number 1
  • Number of Pages XII, 306
  • Number of Illustrations 10 b/w illustrations, 0 illustrations in colour
  • Topics Neurosurgery
  • Buy this book on publisher's site
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