Biological Matrices and Tissue Reconstruction

1. Visceral and Internal Tissues

   1. Co-cultured Human Liver Epithelial Cells in Collagen Gel: A Source for Tissue Engineering in Vitro

      • M. K. H. Auth, R. Joplin, R. Blaheta, A. Encke, P. McMaster, A. J. Strain

      Pages 135-142

   2. Clinical Use of Autologous Endothelial Cell-Seeded PTFE Vascular Grafts for Coronary Artery Revascularization

      • H. R. Laube, J. Duwe, F. X. Kleber, W. Konertz

      Pages 143-151

   3. Influence of Fibrinogen Adhevises and their Components on Growth and Attachment of Human Endothelial Cells

      • A. Bader, B. Stitz, H. A. Henrich

      Pages 153-159

2. Cartilage

   1. Front Matter

      Pages 161-161

      PDF

   2. The Effect of Long-term Culture on the Ability of Human Auricular Chondrocytes to Generate Tissue Engineered Cartilage

      • A. Rodriguez, S. Pap, C. A. Vacanti

      Pages 163-168

   3. Tissue Engineered Cartilage with Cultured Chondrocytes and a Collagen Sponge Matrix

      • C. Klemt

      Pages 169-172

   4. Chondrocyte Differentiation in Fibrin-Coating on Polytetrafluorethylene Membranes

      • P. Angele, A. Nerlich, R. Kujat, H. Faltermeier, H. D. Möller, B. Weigel et al.

      Pages 173-177

   5. In vitro Engineered Cartilage for Reconstructive Surgery, Using Biocompatible, Resorbable Fibrin Glue/Polymer Structures

      • A. Haisch, T. Rathert, O. Schultz, V. Jahnke, G. R. Burmester, M. Sittinger

      Pages 179-187

   6. Autologous Chondrocyte Transplantation: Chondrocyte Culturing and Clinical Aspects

      • C. Erggelet, M. Steinwachs

      Pages 189-193

3. Bone

   1. Front Matter

      Pages 195-195

      PDF

   2. Matrix and Carrier Materials for Bone Growth Factors: State of the Art and Future Perspectives

      • D. Hutmacher, A. Kirsch, K. L. Ackermann, M. B. Hürzeler

      Pages 197-206

   3. Delivery Systems for Osteoinductive Proteins

      • G. Hotz

      Pages 207-213

4. Muscle, Nerves and Tendons

   1. Front Matter

      Pages 215-215

      PDF

   2. Tissue Engineering of Skeletal Muscle Using Micropatterned Biomaterials

      • T. O. Acarturk, P. C. Johnson, P. A. DiMilla

      Pages 217-223

   3. Tissue Engineered Nerve Conduits: The Use of Biodegradable Poly-DL-lactic-co-glycolic Acid (PLGA) Scaffolds in Peripheral Nerve Regeneration

      • G. R. D. Evans, K. Brandt, M. Widmer, A. Gürlek, T. Savel, P. Gupta et al.

      Pages 225-235

   4. Tissue Engineered Collagen Nerve Guidance Channels

      • H. E. McDaniel Jr.

      Pages 237-241

   5. The Role of Fibrin Glue as a Provisional Matrix in Tendon Healing

      • M. Holch, A. Bienwener, H. Thermann, H. Zwipp

      Pages 243-252

5. Vario

   1. Front Matter

      Pages 253-253

      PDF

   2. Wound Healing, Fluid and Protein Balance in Severe Burns Following Topical Application of Clotting Factors

      • A. Bader, F. Bäumer, H. A. Henrich

      Pages 255-262

   3. Primary Human Osteoblast Cultures on Different Biomaterials — Tissue-Engineering for Bone Reconstruction

      • D. J. Schaefer, B. Munder, G. B. Stark

      Pages 263-266

C.A. VACANTI The loss or failure of an organ or tissue is one of the most frequent, devastating, and costly problems in human health care. Advances in the medical sciences have enabled physicians to restore lost functions in their patients through or­ gan transplantation, reconstructive surgery with autogenous tissue transfer, or the implantation of alloplastic materials. Although only recently termed "Tissue Engineering" [1], the use of biological andlor synthetic materials in conjunction with cells to create biologic substitutes to serve as functional tis­ sue replacements has been explored by modern scientists for several decades. The concept of generating functional tissue from an organ biopsy was de­ scribed very early in the literature: "The Lord God cast a deep sleep on the man, and while he was asleep, he took out one of his ribs and closed up its place with flesh. The Lord God then built up into a woman the rib that he had taken from the man" [2]. Review of history further reveals that, according to legend, the first homotransplantation of an entire limb was performed by Saints Damian and Cosmas, as depicted by the artist Fra Angelico.

• burns
• gene therapy
• implant
• skin
• surgery
• therapy
• transplantation

• Abt. Plastische und Handchirurgie, Chirurgische Universitätsklinik Freiburg, Freiburg, Germany

  G. Björn Stark, Raymund Horch, Eszter TÁczos

Policies and ethics