© 1999

Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic

  • J. Grafman
  • Yves Christen
Conference proceedings

Part of the Research and Perspectives in Neurosciences book series (NEUROSCIENCE)

Table of contents

  1. Front Matter
    Pages I-XI
  2. R. Melzack, T. J. Coderre, A. L. Vaccarino, J. Katz
    Pages 35-52
  3. L. G. Cohen, R. Chen, P. Celnik
    Pages 65-77
  4. A. Pascual-Leone, R. Hamilton, J. M. Tormos, J. P. Keenan, M. D. Catalá
    Pages 93-108
  5. J. Grafman, I. Litvan
    Pages 131-139
  6. R. S. J. Frackowiak
    Pages 141-156
  7. Back Matter
    Pages 189-191

About these proceedings


Neuronal Plasticity: Building a bridge from the laboratory to the clinic arrives at an opportune time in the history of the neurological sciences. Over the last twenty years there has been an explosive growth in our understanding of the molecular, cellular, and anatomical changes that occur in the days and weeks following brain injury. It is now clear that training and exposure to certain environments can modify and shape neuronal plasticity in lower animals and humans. In humans, in particular, there are new ways of charting neuronal plasticity at the ensemble or regional level using functional neuroimaging techniques such as positron emission tomography and functional magnetic resonance imaging. Transcranial magnetic stimulation is a technique that can be used to both chart and facilitate/inhibit neuronal plasticity and has been used with much recent success. The design of neuroplasticity experiments and the methods used to interpret findings have also become more sophisticated. Thus, the time seems right for transporting the laboratory results to the clinic so that experimental findings can be tested in the "field". In general, there has been a rather slow absorption of the experimental findings in rehabilitation medicine. This volume provides some impetus to moving the field of cognitive neuroscience a little further among in its efforts to improve the lives of patients who have suffered a debilitating brain injury.


Brain damage Cognitive Neuroscience amputees-brain plasticity in adults brain brain injury cognition development functional magnetic resonance magnetic resonance imaging (MRI) motor representations neuroscience perception positron emission tomography positron emission tomography (PET)

Editors and affiliations

  • J. Grafman
    • 1
  • Yves Christen
    • 2
  1. 1.Cognitive Neuroscience Section, Medical Neurology Branch, National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesdaUSA
  2. 2.Pour la Recherche ThérapeutiqueFondation IPSENParis Cedex 16France

Bibliographic information

  • Book Title Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic
  • Editors Jordan Grafman
  • Series Title Research and Perspectives in Neurosciences
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-64357-9
  • Softcover ISBN 978-3-642-64172-5
  • eBook ISBN 978-3-642-59897-5
  • Series ISSN 0945-6082
  • Edition Number 1
  • Number of Pages XI, 191
  • Number of Illustrations 44 b/w illustrations, 11 illustrations in colour
  • Topics Neurosciences
    Animal Physiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals