Mitochondrial Diseases

Models and Methods

  • Patrick Lestienne

Table of contents

  1. Front Matter
    Pages I-XI
  2. P. Lestienne
    Pages 1-4
  3. J. Veziers, P. Lestienne
    Pages 5-15
  4. D. Casane, M. Guéride
    Pages 17-31
  5. P. Lestienne, M. F. Bouzidi, Isabelle Desguerre, Gérard Ponsot
    Pages 33-58
  6. C. Florentz, H. Brulé, M. Helm, R. Giegé
    Pages 59-72
  7. H. Duborjal, R. Beugnot, V. Procaccio, J. P. Issartel, J. Lunardi
    Pages 73-86
  8. P. Lestienne, C. Desnuelle
    Pages 87-95
  9. G. Brasseur, P. Brivet-Chevillotte, D. Lemesle-Meunier, J.-P. Di Rago
    Pages 97-113
  10. A. Poyau, C. Godinot
    Pages 115-127
  11. K. Buchet, C. Godinot
    Pages 129-142
  12. C. Fiore, V. Trezeguet, C. Schwimmer, P. Roux, R. Noel, A. C. Dianoux et al.
    Pages 143-158
  13. E. Clottes, O. Marcillat, M. J. Vacheron, C. Leydier, C. Vial
    Pages 159-172
  14. C. Marsac, D. François, F. Fouque, C. Benelli
    Pages 173-184
  15. J. Coppey, C. Durieux, M. Coppey-Moisan
    Pages 185-196
  16. S. Alziari, N. Petit, E. Lefai, F. Beziat, P. Lecher, S. Touraille et al.
    Pages 197-208
  17. L. Belcour, A. Sainsard-Chanet, C. Jamet-Vierny, M. Picard
    Pages 209-228
  18. P. Lestienne, J. Veziers
    Pages 229-238
  19. B. Mignotte, G. Kroemer
    Pages 239-254
  20. C. Wrutniak, P. Rochard, F. Casas, G. Cabello
    Pages 255-270
  21. J.-F. Leterrier, M. Lindén
    Pages 271-281
  22. I. A. Tarassov, N. S. Entelis, R. P. Martin
    Pages 303-316
  23. L. Maréchal-Drouard, A. Dietrich, H. Mireau, N. Peeters, I. Small
    Pages 317-326
  24. S. Litvak, M. Hernould, E. Zabaleta, V. Blanc, D. Begu, I. Kurek et al.
    Pages 327-341
  25. N. B. Romero, M. Coquet, H. Carrier
    Pages 343-355
  26. M. Malgat, T. Letellier, G. Durrieu, J.-P. Mazat
    Pages 357-377
  27. P. Reynier, Y. Malthièry, P. Lestienne
    Pages 379-387
  28. Back Matter
    Pages 389-396

About this book


This volume covers the molecular aspects of mitochondrial disorders and their diagnosis with particular emphasis on the mitochondrial tRNA structure and its various mutations. It further describes some key nuclear-encoded proteins involved in energy transduction and presents new aspects of mitochondrial DNA, e.g. its in vivo conformational changes, and models of deletions and partition. Moreover, it discusses the involvement of mitochondria in apoptosis, hormonal response and ageing. This volume also investigates the precise molecular import mechanisms of particular proteins and specific tRNAs into plants and yeast mitochondria relevant to human diseases.


ATP DNA DNA analysis Termination apoptosis cytoskeleton enzyme evolution genome mitochondria mutation physiology protein proteins tRNA

Editors and affiliations

  • Patrick Lestienne
    • 1
  1. 1.E 99-29 INSERM, Physiologie MitochondrialeUniversité Victor Segalen Bordeaux 2Bordeaux CedexFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-64166-4
  • Online ISBN 978-3-642-59884-5
  • Buy this book on publisher's site
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