Signaling Through the Cell Matrix

  • Alvaro Macieira-Coelho

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 25)

Table of contents

  1. Front Matter
    Pages I-X
  2. Maria José Gómez-Lechón, Ramiro Jover, Teresa Donato, Xavier Ponsoda, José V. Castell
    Pages 89-104
  3. Leen Van Hoorde, Elisabeth Van Aken, Marc Mareel
    Pages 105-134
  4. Back Matter
    Pages 135-136

About this book


This book covers a hot subject in cell biology; i.e. how the cell environment sends messages to the cell, regulates gene expression, and modulates the cell phenotype. For a long time the extracellular matrix was believed to have only a supporting role for cell attachement. However, it became apparent that the matrix participates actively in cell metabolism. The experiments that led to this conclusion are described in this volume. Progressively, molecules have been identified that transmit this signaling at the cell-matrix interface. Their identity and mechanism of action are also illustrated in this book. Finally, it explains the role the cell-matrix relationship plays in the regulation of cell proliferation, cell differentiation, and the expression of malignancy.


Activation cancer cell cell biology cell differentiation cellular differentiation enzyme gene gene expression genome liver metabolism regulation topology transcription

Editors and affiliations

  • Alvaro Macieira-Coelho
    • 1
  1. 1.University of Paris VIVersaillesFrance

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-67220-3
  • Online ISBN 978-3-642-59766-4
  • Series Print ISSN 0079-6484
  • Buy this book on publisher's site
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