Microanatomy and Function of the Spleen

  • Birte Steiniger
  • Peter Barth

Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 151)

Table of contents

  1. Front Matter
    Pages I-IX
  2. Birte Steiniger, Peter Barth
    Pages 1-2
  3. Birte Steiniger, Peter Barth
    Pages 3-8
  4. Birte Steiniger, Peter Barth
    Pages 9-23
  5. Birte Steiniger, Peter Barth
    Pages 25-44
  6. Birte Steiniger, Peter Barth
    Pages 45-63
  7. Birte Steiniger, Peter Barth
    Pages 65-67
  8. Birte Steiniger, Peter Barth
    Pages 73-80
  9. Birte Steiniger, Peter Barth
    Pages 81-83
  10. Birte Steiniger, Peter Barth
    Pages 85-97
  11. Back Matter
    Pages 99-101

About this book


This publication provides the first comprehensive review of human splenic microanatomy in correlation with up-to-date information on the immunological function of different splenic compartments. The authors provide an inter-species comparison of splenic microstructure in humans and rats to highlight the species-specific peculiarities of human spleens revealed by immunohistology. The finer structure of human B- and T-cell compartments and their surroundings is defined in detail based on the nomenclature established in rodent immunology. The authors review the typical microscopical features of an antibody response in the spleen of rodents. All information on vascular structures, lymphocytes, special macrophage and fibroblast populations is finally integrated into a hypothesis of lymphocyte recirculation through the human spleen.


Antigen Chemokine Migration human spleen immunohistology microanatomy rat spleen splenic function

Authors and affiliations

  • Birte Steiniger
    • 1
  • Peter Barth
    • 2
  1. 1.Institut für Anatomie und ZellbiologieMarburgGermany
  2. 2.Medizinisches Zentrum für PathologieMarburgGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-66161-0
  • Online ISBN 978-3-642-57088-9
  • Series Print ISSN 0301-5556
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals