Nitric Oxide

  • Bernd Mayer

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 143)

Table of contents

  1. Front Matter
    Pages I-XXIX
  2. Introduction

    1. S. Moncada
      Pages 1-3
  3. Chemistry

    1. Front Matter
      Pages 5-5
    2. D. A. Wink, K. M. Miranda, M. G. Espey, J. B. Mitchell, M. B. Grisham, J. Fukuto et al.
      Pages 7-29
  4. Biochemistry and Pharmacology of NO Synthesis and Action

    1. Front Matter
      Pages 31-31
    2. D. J. Stuehr, S. Ghosh
      Pages 33-70
    3. D. Koesling, A. Friebe
      Pages 93-109
    4. E. R. Werner, H. H. H. W. Schmidt
      Pages 137-158
    5. B. BrüNe, A. Von Knethen, K. Sandau
      Pages 159-175
  5. Physiological Functions of NO

    1. Front Matter
      Pages 177-177
    2. R. Busse, I. Fleming
      Pages 179-206
    3. J.-L. Balligand
      Pages 207-234
    4. L. McNaughton, A. Radomski, G. Sawicki, Marek W. Radomski
      Pages 235-257
    5. P. Navarra, A. Costa, A. Grossman
      Pages 315-328
    6. E. Hackenthal
      Pages 329-361
  6. The Role of Pharmacological Action of NO in Human Disease

    1. Front Matter
      Pages 363-363
    2. P. Vallance, D. Rees, S. Moncada
      Pages 385-397
    3. D. Keh, H. Gerlach, K. Falke
      Pages 399-441
    4. R. Zamora, T. R. Billiar
      Pages 493-523
    5. P. A. MacCarthy, A. M. Shah
      Pages 545-570
    6. H. Bult, K. E. Matthys, M. M. Kockx
      Pages 571-617
    7. M. Sasaki, T. M. Dawson, V. L. Dawson
      Pages 619-637
    8. H. E. von der Leyen, V. J. Dzau
      Pages 639-653
  7. Back Matter
    Pages 655-667

About this book


Nitric oxide (NO) has been discovered to play a fundamental role in a number of biological phenomena. This book describes various aspects of nitric oxide biology, physiology and pharmacology. It is divided into three sections. The first part deals with the basic chemistry and enzymology of NO, thus laying a molecular basis for what follows. The middle part surveys the physiological roles of NO under normal conditions. The concluding part explores the relevance of NO to disease, both as a pathogenic factor and a therapeutic target. The book thus provides detailed information on NO biology to the reader unfamiliar with the field and represents a reference work for scientists working in an NO-related field of biomedical research. Each chapter, written by experts in their fields, gives a broad introduction followed by a comprehensive review of the current knowledge and a detailed reference list.


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Editors and affiliations

  • Bernd Mayer
    • 1
  1. 1.Department of Pharmacology and ToxicologyKarl-Franzens-University of GrazGrazAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63026-2
  • Online ISBN 978-3-642-57077-3
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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