Endothelin and Its Inhibitors

  • Timothy D. Warner

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 152)

Table of contents

  1. Front Matter
    Pages I-XXIV
  2. P. J. Henry, R. G. Goldie
    Pages 69-114
  3. M. S. Simonson
    Pages 115-140
  4. H. Kurihara, Y. Kurihara, Y. Yazaki
    Pages 141-154
  5. B. Battistini, A. Y. Jeng
    Pages 155-208
  6. J. D. Elliott, J.-N. Xiang
    Pages 239-270
  7. S. J. Morgan, P. K. Cusick, B. A. Trela
    Pages 271-275
  8. P. D’Orléans-Juste, G. Bkaily, M. Duval, J. Labonté, M. Plante, G. Cournoyer et al.
    Pages 277-298
  9. J. R. Wu-Wong, T. J. Opgenorth
    Pages 299-322
  10. R. G. Goldie, P. J. Henry
    Pages 357-387
  11. D. J. Stewart, Y. D. Zhao
    Pages 389-404
  12. S. A. Douglas, E. H. Ohlstein
    Pages 405-451
  13. D. M. Pollock
    Pages 477-501
  14. Back Matter
    Pages 521-532

About this book


Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.


Circulation Endothelin Glatte Muskulatur Kreislauf Peptide Peptides Smooth Muscle endothelium tissue

Editors and affiliations

  • Timothy D. Warner
    • 1
  1. 1.Department of Cardiac, Vascular and Inflammation ResearchThe William Harvey Research Institute St. Barthomew’s and the Royal London School of Medicine and DentistryLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63237-2
  • Online ISBN 978-3-642-56899-2
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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