© 2001

Immobilized Cells

  • René H. Wijffels

Part of the Springer book series (SLM)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Introduction

  3. Immobilization

    1. Emily J. T. M. Leenen
      Pages 6-14
    2. Denis Poncelet, Claire Dulieu, Muriel Jacquot
      Pages 15-30
    3. Erik Van Zessen, Johannes Tramper, Arjen Rinzema
      Pages 31-35
    4. Emily J. T. M. Leenen
      Pages 36-43
    5. Evelien E. Beuling
      Pages 44-64
  4. Kinetics

    1. Ellen A. Meijer, René H. Wijffels
      Pages 65-73
    2. René H. Wijffels
      Pages 74-76
    3. René H. Wijffels
      Pages 77-84
    4. Dirk De Beer
      Pages 85-100
    5. René H. Wijffels
      Pages 101-122
    6. Jean-Noël Barbotin, Jean-Charles Portais, Paula M. Alves, Helena Santos
      Pages 123-138
  5. Engineering

    1. Denis Poncelet, Stephane Desobry, Ulrich Jahnz, K. Vorlop
      Pages 139-149
    2. René H. Wijffels
      Pages 162-174
    3. Erik Van Zessen, Johannes Tramper, Arjen Rinzema
      Pages 175-181
    4. René H. Wijffels
      Pages 182-190
    5. Emily J. T. M. Leenen
      Pages 191-198
  6. Cases

About this book


Immobilized cells have been studied widely in the last few decades, and an enormous number of papers have been published on this topic. For many processes the complex physiology in a heterogeneous environment is now becoming clear. In addition it has been shown that in many processes it is more efficient to use immobilized cells than suspended cells. The contributions in this volume by scientists from various disciplines in academia, industry and research institutes cover the path from basic physiological research to actual application. One of the goals was to extract guidelines for characterizing immobilized cells in view of process design and application. It is important to recognize that research on immobilized metabolizing cells should eventually lead, whenever possible, to successful implementation of such catalysts in industrial processes, and so one of the aims of using these guidelines is to ensure that research is effective in achieving this objective. A structure was chosen in which general aspects of immobilization as well as kinetics and engineering aspects were covered. Besides laboratory methods, some simple calculation procedures have been presented in this lab manual. The combination of the practical methods with the calculations provide a tool for research with immobilized cells. Finally, the manual concludes with some recent promising and practical cases of immobilized cells as examples of potential applications.


Bioremediation Immobilized cells Metabolite biomass concentration biomass gradients gel bead particles material stability measurement of density resonance nozzle technique

Editors and affiliations

  • René H. Wijffels
    • 1
  1. 1.Food and Bioprocess Engineering GroupWageningen UniversityWageningenThe Netherlands

Bibliographic information

  • Book Title Immobilized Cells
  • Editors Rene H. Wijffels
  • Series Title Springer
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-642-47735-5
  • eBook ISBN 978-3-642-56891-6
  • Edition Number 1
  • Number of Pages VIII, 261
  • Number of Illustrations 72 b/w illustrations, 2 illustrations in colour
  • Topics Cell Biology
    Food Science
  • Buy this book on publisher's site
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