Pharmacology of GABA and Glycine Neurotransmission

  • Hanns Möhler

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 150)

Table of contents

  1. Front Matter
    Pages I-XXI
  2. Physiology of the Neurotransmitters GABA and Glycine

    1. Front Matter
      Pages 1-1
    2. B. E. Alger, F. E. N. Le Beau
      Pages 3-76
  3. Pharmacology of the GABA System

    1. Front Matter
      Pages 77-77
    2. GABAA Receptors

      1. J. J. Lambert, J. A. Peters, S. C. Harney, D. Belelli
        Pages 117-140
      2. M. D. Krasowski, R. A. Harris, N. L. Harrison
        Pages 141-172
      3. B. S. Meldrum, P. Whiting
        Pages 173-194
      4. T. G. Smart, P. Thomas, N. J. Brandon, S. J. Moss
        Pages 195-225
      5. H. Y. Kim, R. W. Olsen
        Pages 251-270
      6. J. Bormann, A. Feigenspan
        Pages 271-296
    3. GABAB Receptors

      1. B. Bettler, K. Kaupmann
        Pages 299-309
      2. N. G. Bowery
        Pages 311-328
      3. S. J. Enna
        Pages 329-342
    4. GABA Transporters

      1. B. I. Kanner
        Pages 345-354
      2. J. E. Clark, W. A. Clark
        Pages 355-372
  4. Pharmacology of the Glycine System

    1. Front Matter
      Pages 373-373
  5. Back Matter
    Pages 403-413

About this book


Highlighting the current developments and future directions in GABA and glycine research, this volume covers the major inhibitory neurotransmitters from the molecular mechanisms of signal transduction to their role in health and disease. It is of topical importance because these neurotransmitters are essential for brain function and therapy of diseases such as anxiety disorders, insomnias, epilepsy, depression, spasticity, and memory deficits. Distinguished scientists at the forefront of research contributed reviews on the role of these transmitters in governing neuronal networks, their signalling pathways, their receptors, the pharmacology of GABA A- and GABA B- and GABA C-receptors as well as of GABA- and glycine-transporters, and their role in disease. The volume serves as reference for pharmacologists/toxicologists, neuroscientists, neurologists and psychiatrists.


Depression GABA Glycine Glycinstoffwechsel Inhibitory neurotransmitters Neurotransmitter pathophysiology physiology

Editors and affiliations

  • Hanns Möhler
    • 1
  1. 1.Institute of Pharmacology and ToxicologyETH and University of ZürichZürichSwitzerland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63191-7
  • Online ISBN 978-3-642-56833-6
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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