© 2001

Cooperation of Liver Cells in Health and Disease


Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 161)

Table of contents

  1. Front Matter
    Pages N2-XII
  2. Introduction — Morphology of the Liver Lobule

  3. Cells of the Liver Lobule

    1. Front Matter
      Pages 7-7
    2. Zbigniew Kmieć
      Pages 9-12
    3. Zbigniew Kmieć
      Pages 13-19
    4. Zbigniew Kmieć
      Pages 21-28
    5. Zbigniew Kmieć
      Pages 29-39
    6. Zbigniew Kmieć
      Pages 41-46
  4. Cross-Talk of Liver Cells in Physiology and Pathology

  5. Back Matter
    Pages 115-151

About this book


The book is the first monograph that describes the importance of the interactions between hepatocytes and nonparenchymal liver cells for the functions of both normal and diseased liver. The concise description of major types of non-hepatocytes (sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes) has been followed by the presentation of the role of cellular cross-talks for the physiological regulation of specific liver functions such as uptake and storage of vitamin A, modulation of glucose homeostasis, sinusoidal blood flow regulation, synthesis of eicosanoids, nitric oxide, and growth factors. The functioning of complicated intercellular networks during the course of endotoxin-induced liver damage, and development of liver fibrosis has also been presented.


Kupffer cells Liver cell cooperation cells endothelium endotoxic liver injury hepatic stellate cells intrahepatic lymphocytes liver fibrosis nonparenchymal liver cells physiology regulation

Authors and affiliations

  1. 1.Department of Histology and ImmunologyMedical University of GdanskGdanskPoland

Bibliographic information

  • Book Title Cooperation of Liver Cells in Health and Disease
  • Authors Z. Kmiec
  • Series Title Advances in Anatomy Embryology and Cell Biology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-540-41887-0
  • eBook ISBN 978-3-642-56553-3
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages XIII, 151
  • Number of Illustrations 18 b/w illustrations, 0 illustrations in colour
  • Topics Life Sciences, general
    Human Physiology
    Cell Biology
  • Buy this book on publisher's site
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