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Single Molecule Spectroscopy

Nobel Conference Lectures

  • Rudolf Rigler
  • Michel Orrit
  • Thomas Basché
Book

Part of the Springer Series in Chemical Physics book series (CHEMICAL, volume 67)

Table of contents

  1. Front Matter
    Pages i-xviii
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  2. History of Optical Trapping and Manipulation of Small Neutral Particles, Atoms, and Molecules
    A. Ashkin
    Pages 1-31
  3. Thirteen Years of Single-Molecule Spectroscopy in Physical Chemistry and Biophysics
    W. E. Moerner
    Pages 32-61
  4. The Electronic Structure of Single Photosynthetic Pigment-Protein Complexes
    A. M. van Oijen, M. Ketelaars, J. Köhler, T. J. Aartsma, J. Schmidt
    Pages 62-81
  5. Single-Molecule Optical Switching: A Mechanistic Study of Nonphotochemical Hole-Burning
    F. Kulzer, T. Basché
    Pages 82-98
  6. Triggered Emission of Single Photons by a Single Molecule
    C. Brunel, P. Tamarat, B. Lounis, M. Orrit
    Pages 99-113
  7. Photophysics of Conjugated Polymers Unmasked by Single Molecule Spectroscopy
    J. Yu, D.-H. Hu, P. F. Barbara
    Pages 114-129
  8. Confining and Probing Single Molecules in Synthetic Liposomes
    C. F. Wilson, D. T. Chiu, R. N. Zare, A. Strömberg, A. Karlsson, O. Orwar
    Pages 130-143
  9. Single Molecule Detection Using Near Infrared Surface-Enhanced Raman Scattering
    K. Kneipp, H. Kneipp, I. Itzkan, R. R. Dasari, M. S. Feld
    Pages 144-160
  10. Single-Molecule Fluorescence — Each Photon Counts
    C. G. Hübner, V. Krylov, A. Renn, P. Nyffeler, U. P. Wild
    Pages 161-176
  11. Fluorescence Correlation Spectroscopy in Single-Molecule Analysis: Enzymatic Catalysis at the Single Molecule Level
    R. Rigler, L. Edman, Z. Földes-Papp, S. Wennmalm
    Pages 177-194
  12. The Characterization of a Transmembrane Receptor Protein by Fluorescence Correlation Spectroscopy
    T. Wohland, K. Friedrich-Bénet, H. Pick, A. Preuss, R. Hovius, H. Vogel
    Pages 195-210
  13. Applications of Dual-Color Confocal Fluorescence Spectroscopy in Biotechnology
    A. Koltermann, U. Kettling, J. Stephan, M. Rarbach, T. Winkler, M. Eigen
    Pages 211-226
  14. Single-Molecule Enzymology
    X. S. Xie, H. P. Lu
    Pages 227-240
  15. Single-Molecule Enzymology
    N. J. Dovichi, R. Polakowski, A. Skelley, D. B. Craig, J. Wong
    Pages 241-256
  16. The Energy Landscape
    H. Frauenfelder, B. H. McMahon
    Pages 257-276
  17. Coherent Intramolecular Dynamics in Small Enzyme Populations
    A. S. Mikhailov, P. Stange, B. Hess
    Pages 277-292
  18. Single-Molecule Dynamics in Biosystems
    T. Yanagida
    Pages 293-312
  19. Single-Molecule Dynamics Associated with Protein Folding and Deformations of Light-Harvesting Complexes
    D. S. Talaga, Y. Jia, M. A. Bopp, A. Sytnik, W. A. DeGrado, R. J. Cogdell et al.
    Pages 313-325
  20. The Study of Single Biomolecules with Fluorescence Methods
    T. Ha, X. Zhuang, H. Babcock, H. Kim, J. W. Orr, J. R. Williamson et al.
    Pages 326-337
  21. Studying the Green Fluorescent Protein with Single-Molecule Spectroscopy
    A. Zumbusch, G. Jung, C. Bräuchle
    Pages 338-352
  22. Back Matter
    Pages 353-355
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About this book

Introduction

This book surveys recent advances related to the application of single molecule techniques in various fields of science. The topics, each described by leading experts in the field, range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics. A unifying theme of all chapters is the power of single molecule techniques to unravel fluctuations and heterogeneities usually hidden in the ensemble average of complex systems. The concept for the book originated from a gathering of some of the world's leading scientists at the Nobel Conference in Sweden.

Keywords

Fluorescence Optical microscopy Single molecules biophysics chemistry enzymes membrane microscopy molecule optics particles physical chemistry protein scattering spectroscopy

Authors and affiliations

  • Rudolf Rigler
    • 1
  • Michel Orrit
    • 2
  • Thomas Basché
    • 3
  1. 1.Department of Medical BiophysicsKarolinska InstitutetStockholmSweden
  2. 2.CNRS et Université Bordeaux IC.P.M.O.H.TalenceFrance
  3. 3.Institut für Physikalische ChemieJohannes Gutenberg-UniversitätMainzGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-56544-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62702-6
  • Online ISBN 978-3-642-56544-1
  • Series Print ISSN 0172-6218
  • Buy this book on publisher's site