Cerebral Blood Flow

Mechanisms of Ischemia, Diagnosis, and Therapy

  • Michael R. Pinsky

Part of the Update in Intensive Care Medicine book series (volume 37)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Physiology and Pathophysiology

    1. Front Matter
      Pages 1-1
    2. Walter D. Obrist
      Pages 3-6
    3. Costantino Iadecola, Kiyoshi Niwa
      Pages 7-16
    4. Amin B. Kassam, David G. Peters, Michael B. Horowitz
      Pages 26-41
  3. Ischemic Brain Injury

    1. Front Matter
      Pages 43-43
    2. Bo K. Siesjö, Tibor Kristián, Hiroyuki Uchino
      Pages 45-59
    3. Patrick M. Kochanek, Kristy S. Hendrich, Kimberly D. Statler, Robert S.B. Clark, Larry W. Jenkins, Donald S. Williams et al.
      Pages 60-71
    4. Steven H. Graham, Robert W Hickey
      Pages 96-105
    5. Konstantin-Alexander Hossmann
      Pages 137-146
  4. Assessment of Cerebral Blood Flow

    1. Front Matter
      Pages 147-147
    2. F.A. Pennings, G.J. Bouma, Can Ince
      Pages 149-164
    3. George Hunter, Leena M. Hamberg, Michael H. Lev, Ramon Gilberto Gonzales
      Pages 165-178
    4. M. Moonis, Majaz Moonis, Marc Fisher
      Pages 191-200
    5. Viken Babikian, Joao Gomes, Jaroslaw Krejza
      Pages 201-216
  5. Current Status of Clinical Trials in Acute Stroke

    1. Front Matter
      Pages 227-227
    2. Lawrence R. Wechsler
      Pages 229-235
    3. Alastair M. Buchan
      Pages 236-251
    4. Randall T. Higashida, Christopher F. Dowd, Van V. Halbach, Adel M. Malek, Constantine C. Phatouros
      Pages 252-271
    5. Donald W. Marion
      Pages 272-276
  6. Back Matter
    Pages 299-308

About this book


Cerebral Blood Flow: Quantifying Consciousness Although the heart may be the source of energy needed to generate blood flow,and other organs absolutely essential for normal living,the brain is the reason we are alive. The collected book chapters are aimed at addressing this most fundamental organ and its blood flow. These papers reflect detailed descriptions of similar topics presented over a two-day period as part of the 5th International Symposium on Applied Physiology of the Peripheral Circulation held in Pittsburgh, Pennsylvania, in June 2000. The symposium and this volume were organized into four distinct groupings that follow in a logical fashion. The initial papers focus on the basic unique physiology and pathophysiology of the cerebral circulation, including a historical reviewof the means to measure cerebral blood flow and its implications of the past 30 years. Dr. Walter D. Obrist was one of the original investigators to use radiolabeled markers to assess cerebral blood flow. His equations and initial studies form an impressive introduction to where we are now. As with much of the body's special organs, the brain too has many circulatory features unique to itself.These include the unique blood-brain barrier function ofthe endothelium, local neural regulation control, and intracranial pressure effects. These special issues,plus genetic factors that may predispose individuals to developing cere­ bral aneurysm, make up the initial section of the monograph.


PET Trauma acute stroke aneurysm brain brain injury cerebral ischemia cerebral resuscitation hemodynamics ischemia neuroradiology pathophysiology positron emission tomography (PET) radiology traumatic brain injury

Authors and affiliations

  • Michael R. Pinsky
    • 1
  1. 1.Department of Anesthesiology and Critical Care MedicineUniversity of PittsburghPittsburghUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2002
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-42684-4
  • Online ISBN 978-3-642-56036-1
  • Series Print ISSN 0933-6788
  • Buy this book on publisher's site
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