Jaagsiekte Sheep Retrovirus and Lung Cancer

  • Hung Fan

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 275)

Table of contents

  1. Front Matter
    Pages I-XI
  2. M. De Las Heras, L. González, J. M. Sharp
    Pages 25-54
  3. J. M. Sharp, J. C. DeMartini
    Pages 55-79
  4. M. Palmarini, H. Fan
    Pages 81-115
  5. J. C. DeMartini, J. O. Carlson, C. Leroux, T. Spencer, M. Palmarini
    Pages 117-137
  6. H. Fan, M. Palmarini, J. C. DeMartini
    Pages 139-177
  7. M. De las Heras, A. Ortín, C. Cousens, E. Minguijón, J. M. Sharp
    Pages 201-223
  8. J.-F. Mornex, F. Thivolet, M. De Las Heras, C. Leroux
    Pages 225-248
  9. Back Matter
    Pages 249-252

About this book


Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.


AIDS diseases gene gene therapy leukemia maedi virus molecular biology oncogenesis ovine pulmonary adenocarcinoma pathology retroviruses reverse transcriptase virus visna virus

Editors and affiliations

  • Hung Fan
    • 1
  1. 1.Cancer Research InstituteUniversity of California, IrvineIrvineUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62897-9
  • Online ISBN 978-3-642-55638-8
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site
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