Guidance Cues in the Developing Brain

  • Ivica Kostović

Part of the Progress in Molecular and Subcellular Biology book series (PMSB, volume 32)

Table of contents

  1. Front Matter
    Pages I-XII
  2. M. Judaš, N. J. Milošević, M.-R. Rašin, M. Heffer-Lauc, I. Kostović
    Pages 1-32
  3. R. Mendez-Otero, L. A. Cavalcante
    Pages 97-124
  4. Back Matter
    Pages 143-145

About this book


Many complex molecular interactions are involved in the development of the mammalian brain. Molecules serving as guidance cues for migratory cells, growing axons and for recognition of postsynaptic targets are a major topic for research because they are directly involved in the formation of neuronal circuits, thus creating the foundation for subsequent functional refinement through interactions with the environment. In addition, most guidance cue molecules are also involved in plasticity, damage repair and regeneration in the adult brain.

This volume reviews current knowledge on major classes of molecules involved in: guidance of growing axons; tau proteins involved in the establishment of axonal polarity, outgrowth and contact recognition; gangliosides and lectins involved in neuronal migration, neurite outgrowth and contact recognition; and myelin molecules that inhibit nerve regeneration.


Neuron Regeneration Tempo brain cells cytoskeleton development genes migration morphology post-translational modification protein proteins proteoglycans translation

Editors and affiliations

  • Ivica Kostović
    • 1
  1. 1.Croatian Institute for Brain Research School of MedicineUniversity of ZagrebZagrebCroatia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62426-1
  • Online ISBN 978-3-642-55557-2
  • Series Print ISSN 0079-6484
  • Buy this book on publisher's site