Peptide Growth Factors and Their Receptors I

  • Michael B. Sporn
  • Anita B. Roberts

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 95 / 1)

Table of contents

  1. Front Matter
    Pages I-XXVI
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. M. B. Sporn, A. B. Roberts
      Pages 3-15
    3. R. A. Bradshaw, K. P. Cavanaugh
      Pages 17-36
    4. M. P. Czech, K. B. Clairmont, K. A. Yagaloff, S. Corvera
      Pages 37-65
  3. Individual Growth Factors and Their Receptors

    1. Front Matter
      Pages 67-67
    2. G. Carpenter, M. I. Wahl
      Pages 69-171
    3. E. W. Raines, D. F. Bowen-Pope, R. Ross
      Pages 173-262
    4. M. M. Rechler, S. P. Nissley
      Pages 263-367
    5. A. Baird, P. Böhlen
      Pages 369-418
    6. A. B. Roberts, M. B. Sporn
      Pages 419-472
    7. J. A. Schmidt, M. J. Tocci
      Pages 473-521
    8. M. Hatakeyama, T. Taniguchi
      Pages 523-540
    9. J. N. Ihle
      Pages 541-575
    10. T. Yokota, N. Arai, K.-I. Arai, A. Zlotnik
      Pages 577-607
    11. T. Honjo, K. Takatsu
      Pages 609-632
    12. T. Hirano, T. Kishimoto
      Pages 633-665
    13. S. Nagata
      Pages 699-722
    14. E. Goldwasser, N. Beru, D. Smith
      Pages 747-770
  4. Back Matter
    Pages 771-796

About this book


This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entire field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost impossible for anyone person to stay informed on this subject by reading the primary literature. At the same time it is becoming increasingly apparent that these substances are of universal importance in biology and medicine and that the original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony­ stimulating factors," was quite artifactual; they are in fact the basis of a com­ mon language for intercellular communication. As a set they affect essentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research. This treatise is divided into four main sections. After three introductory chapters, its principal focus is the detailed description of each of the major peptide growth factors in 26 individual chapters.


Zelle biology cell chemistry gene primary structure receptor regulation research tissue

Editors and affiliations

  • Michael B. Sporn
    • 1
  • Anita B. Roberts
    • 1
  1. 1.Laboratory of ChemopreventionNational Cancer InstituteBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-49297-6
  • Online ISBN 978-3-642-49295-2
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site
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