Mechanism of Action of Antimicrobial and Antitumor Agents

  • John W. Corcoran
  • Fred E. Hahn
  • J. F. Snell
  • K. L. Arora

Part of the Antibiotics book series (ANTIBIOTICS, volume 3)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Interference with Nucleic Acid Biosynthesis

    1. Front Matter
      Pages 1-1
    2. Kurt W. Kohn
      Pages 3-11
    3. Harold T. Shigeura
      Pages 12-20
    4. Hamao Umezawa
      Pages 21-33
    5. Susan B. Horwitz
      Pages 48-57
    6. Fred E. Hahn
      Pages 58-78
    7. Fred E. Hahn
      Pages 79-100
    8. Z. Kurylo-Borowska
      Pages 129-140
    9. Michael Waring
      Pages 141-165
    10. Irving H. Goldberg
      Pages 166-173
    11. William A. Goss, Thomas M. Cook
      Pages 174-196
    12. G. F. Gause
      Pages 197-202
    13. Alan David Wolfe
      Pages 203-233
    14. Ken Katagiri, Tadashi Yoshida, Kosaburo Sato
      Pages 234-251
    15. W. Wehrli, M. Staehelin
      Pages 252-268
    16. G. F. Gause
      Pages 269-273
    17. Erich Hirschberg
      Pages 274-302
    18. John W. Corcoran, Fred E. Hahn, J. F. Snell, K. L. Arora
      Pages 302-303
    19. James J. Burchall
      Pages 304-320
  3. Interference with Protein Biosynthesis

    1. Front Matter
      Pages 321-321
    2. Sidney Pestka
      Pages 323-326
    3. Nobuo Tanaka
      Pages 340-364
    4. K. Poralla
      Pages 365-369
    5. Sidney Pestka
      Pages 370-395
    6. Nancy L. Oleinick
      Pages 396-419
    7. Arthur P. Grollman, Zelda Jarkovsky
      Pages 420-435
    8. Nobuo Tanaka
      Pages 436-447
    9. Munehiko Yukioka
      Pages 448-458
    10. D. Vazquez
      Pages 459-479
    11. Sidney Pestka
      Pages 480-486
    12. Nobuo Tanaka
      Pages 487-497
    13. Irving H. Goldberg
      Pages 498-515
    14. John G. Olenick
      Pages 516-520
    15. D. Vazquez
      Pages 521-534
    16. David Schlessinger, Gerald Medoff
      Pages 535-550
    17. Sidney Pestka, James W. Bodley
      Pages 551-573
  4. Interference with Cell Wall/Membrane Biosynthesis, Specific Enzyme Systems and Those in Which Mode of Action Not Known with Certainty

    1. Front Matter
      Pages 575-575
    2. Fred E. Hahn, Jennie Ciak
      Pages 577-584
    3. W. Pache
      Pages 585-587
    4. Louis W. Wendt
      Pages 588-605
    5. Floyd M. Huber
      Pages 606-613
    6. Simon Silver, Louis Wendt, Pinakilal Bhattacharyya
      Pages 614-622
    7. C. R. Krishna Murti
      Pages 623-652
    8. F. Knüsel, W. Zimmermann
      Pages 653-667
    9. Nitya Anand
      Pages 668-698
    10. John G. Olenick
      Pages 699-703

About this book


This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since the appearance of Volume I, also dealing with Mechanism of Action, tremendous strides have been made in the depth and breadth of our knowledge of molecular biology, microbial chemistry and molecular pharmacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti­ biotics in the development of our understanding of nucleic acid synthesis and function and its relationship to protein synthesis and cell physiology has led rapidly to a very precise, understanding of how many of these same antibiotics inhibit susceptible cells.


Antibiotics Antimicrobial Agents Biochemie Krebs biology physiology protein

Editors and affiliations

  • John W. Corcoran
    • 1
  • Fred E. Hahn
    • 2
  • J. F. Snell
  • K. L. Arora
  1. 1.Department of Biochemistry, The Medical and Dental SchoolsNorthwestern UniversityChicagoUSA
  2. 2.Department of the Army, Walter Reed Army Institute of ResearchWalter Reed Army Medical CenterUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1975
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-46306-8
  • Online ISBN 978-3-642-46304-4
  • Buy this book on publisher's site
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