© 1972

Transformations in the Facial Region of the Human Embryo

Conference proceedings

Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 46/5)

Table of contents

  1. Front Matter
    Pages 1-5
  2. Christl Vermeij-Keers
    Pages 7-7
  3. Christl Vermeij-Keers
    Pages 7-10
  4. Christl Vermeij-Keers
    Pages 10-20
  5. Christl Vermeij-Keers
    Pages 20-25
  6. Christl Vermeij-Keers
    Pages 25-26
  7. Back Matter
    Pages 26-30

About these proceedings


The human face is invariably interesting, even as an object of embryologic analysis. The early embryonic growth processes are located around the developing sense organs, among which the nose holds a key position. The first indication of the development of the nose is the formation of the placodes, oval areas of thick­ ened and condensed ectoderm, one on each side of the head. Each of these placodes is transformed, via the nasal groove, into the nasal tube, sometimes indicated as primitive nasal cavity. In the literature this transformation has been described as an isolated process that changes the superficial facial region. Some authors, including Wolgensinger (1950), think that the active component of this trans­ formation primarily is the ectoderm of the nasal placode. Others, i. e. Hochstetter (1891), Kallius (1905) and Vermeij-Keers (1967), assume this component be located in the mesenchyme. Peter (1913, 1949), Patten (1953, 1961), Warbrick (1960), and Andersen and Matthiessen (1967) hold both these components to be active. In the first and last of these three concepts the ectoderm of the nasal placode and the nasal groove respectively, is thought to invade the mesenchyme in the posterior direction. Invading ectoderm has also been considered to form - independent of the transformation - the organ of Jacobson and the naso­ lacrimal duct and to separate the conchae (e. g. Born, 1876; Legal, 1883; Kallius, 1905; Peter, 1913, 1949; Streeter, 1948; Andersen and Matthiessen, 1967).


development embryo growth

Authors and affiliations

  1. 1.Anatomisch-Embryologisch LaboratoriumBoerhaavekwartier, LeidenNederland

Bibliographic information

  • Book Title Transformations in the Facial Region of the Human Embryo
  • Authors C. Vermeij - Keers
  • Series Title Advances in Anatomy, Embryology and Cell Biology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1972
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-3-540-06088-8
  • eBook ISBN 978-3-642-46292-4
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages , 32
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Medicine/Public Health, general
  • Buy this book on publisher's site
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